Valium and Joint contracture - a phase IV clinical study of FDA data

Summary:

Joint contracture is reported as a side effect among people who take Valium (diazepam), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Magnevist, and have Chronic obstructive pulmonary disease.

The phase IV clinical study analyzes which people have Joint contracture when taking Valium. It is created by eHealthMe based on reports of 45,658 people who have side effects when taking Valium from the FDA, and is updated regularly.

What is Valium?

Valium has active ingredients of diazepam. It is often used in stress and anxiety. eHealthMe is studying from 48,647 Valium users. Check the latest studies of Valium.

What is Joint contracture?

Joint contracture (a permanent shortening of a muscle or joint) is found to be associated with 333 drugs and 653 conditions by eHealthMe. Check the latest studies of Joint contracture.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

45,658 people reported to have side effects when taking Valium.
Among them, 25 people (0.05%) have Joint contracture.

Could Valium cause Joint contracture?

Among these 25 people:

How long have people been on Valium when they have Joint contracture? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Joint contracture when taking Valium? *

  • female: 72 %
  • male: 28 %

What is the age of people who have Joint contracture when taking Valium? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 9.09 %
  • 20-29: 4.55 %
  • 30-39: 27.27 %
  • 40-49: 27.27 %
  • 50-59: 31.82 %
  • 60+: 0.0 %

What are other drugs people take besides Valium? *

  1. Magnevist: 17 people, 68.00%
  2. Renagel: 15 people, 60.00%
  3. Protonix: 13 people, 52.00%
  4. Omniscan: 12 people, 48.00%
  5. Aranesp: 11 people, 44.00%
  6. Plavix: 10 people, 40.00%
  7. Folic Acid: 10 people, 40.00%
  8. Venofer: 10 people, 40.00%
  9. Neurontin: 10 people, 40.00%
  10. Dilaudid: 9 people, 36.00%

What are other side effects people have besides Joint contracture? *

  1. Nephrogenic Systemic Fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease): 16 people, 64.00%
  2. Dry Skin: 12 people, 48.00%
  3. Skin Hypertrophy (skin cells enlarges): 12 people, 48.00%
  4. Weakness: 11 people, 44.00%
  5. Skin Tightness: 11 people, 44.00%
  6. Skin Induration (an abnormally hard spot or area on the skin): 11 people, 44.00%
  7. Skin Exfoliation (removal of the oldest dead skin cells): 11 people, 44.00%
  8. Pain: 10 people, 40.00%
  9. Oedema Peripheral (superficial swelling): 8 people, 32.00%
  10. Skin Discoloration: 7 people, 28.00%

What are the existing conditions these people have? *

  1. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 7 people, 28.00%
  2. Nuclear Magnetic Resonance Imaging Brain: 6 people, 24.00%
  3. Diabetes: 6 people, 24.00%
  4. Anaemia (lack of blood): 6 people, 24.00%
  5. Nausea (feeling of having an urge to vomit): 5 people, 20.00%
  6. Hypotension (abnormally low blood pressure): 5 people, 20.00%
  7. Pain: 2 people, 8.00%
  8. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 4.00%
  9. Psychotic Disorder: 1 person, 4.00%
  10. Peripheral Arterial Occlusive Disease (reproducible ischemic muscle pain): 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Valium and have Joint contracture?

- Check whether Joint contracture is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Valium:

Joint contracture treatments and more:

How severe was Joint contracture and when was it recovered:

Expand to all the drugs that have ingredients of diazepam:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Valium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint contracture:

Browse all the conditions that are associated with Joint contracture:


How the study uses the data?

The study uses data from the FDA. It is based on diazepam (the active ingredients of Valium) and Valium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: