Valium and Necrosis - a phase IV clinical study of FDA data
Summary:
Necrosis is reported as a side effect among people who take Valium (diazepam), especially for people who are female, 20-29 old, have been taking the drug for < 1 month also take Lasix, and have Pulmonary embolism.
The phase IV clinical study analyzes which people have Necrosis when taking Valium. It is created by eHealthMe based on reports of 45,658 people who have side effects when taking Valium from the FDA, and is updated regularly.
What is Valium?
Valium has active ingredients of diazepam. It is often used in stress and anxiety. eHealthMe is studying from 48,647 Valium users. Check the latest studies of Valium.
What is Necrosis?
Necrosis (the death of body tissue) is found to be associated with 745 drugs and 970 conditions by eHealthMe. Check the latest studies of Necrosis.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
45,658 people reported to have side effects when taking Valium.
Among them, 30 people (0.07%) have Necrosis.

Among these 30 people:
How long have people been on Valium when they have Necrosis? *
- < 1 month: 50 %
- 1 - 6 months: 50 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Necrosis when taking Valium? *
- female: 80 %
- male: 20 %
What is the age of people who have Necrosis when taking Valium? *
- 0-1: 0.0 %
- 2-9: 5.56 %
- 10-19: 0.0 %
- 20-29: 27.78 %
- 30-39: 11.11 %
- 40-49: 22.22 %
- 50-59: 16.67 %
- 60+: 16.67 %
What are other drugs people take besides Valium? *
- Lasix: 9 people, 30.00%
- Prevacid: 7 people, 23.33%
- Kytril: 6 people, 20.00%
- Aredia: 6 people, 20.00%
- Faslodex: 6 people, 20.00%
- Fioricet: 6 people, 20.00%
- Coumadin: 6 people, 20.00%
- Zometa: 6 people, 20.00%
- Nuvaring: 6 people, 20.00%
- Duragesic-100: 6 people, 20.00%
What are other side effects people have besides Necrosis? *
- Uterine Leiomyoma (uterine benign tumour derived from smooth muscle): 10 people, 33.33%
- Leukocytosis (increased white blood cells): 10 people, 33.33%
- Depression: 8 people, 26.67%
- Anaemia (lack of blood): 7 people, 23.33%
- Abortion Spontaneous (naturally occurring miscarriage): 6 people, 20.00%
- Osteonecrosis Of Jaw (death of bone of jaw): 6 people, 20.00%
- Mucosal Ulceration (ulcers of mucous membrane): 6 people, 20.00%
- Pharyngeal Mass: 6 people, 20.00%
- Mucosal Inflammation (infection of mucous membrane): 6 people, 20.00%
- Joint Pain: 6 people, 20.00%
What are the existing conditions these people have? *
- Birth Control: 6 people, 20.00%
- Pulmonary Embolism (blockage of the main artery of the lung): 6 people, 20.00%
- Migraine (headache): 3 people, 10.00%
- High Blood Pressure: 2 people, 6.67%
- Breast Cancer: 2 people, 6.67%
- Burkitt Lymphoma (cancer of the lymphatic system): 2 people, 6.67%
- Osteoporosis (bones weak and more likely to break): 2 people, 6.67%
- Depression: 2 people, 6.67%
- Bronchitis Chronic (inflammation of the mucous membrane in the bronchial tubes- chronic): 1 person, 3.33%
- Cardiac Failure: 1 person, 3.33%
* Approximation only. Some reports may have incomplete information.
Do you take Valium and have Necrosis?
- Check whether Necrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Valium:
- Valium (48,647 reports)
Necrosis treatments and more:
- Necrosis (8,274 reports)
How severe was Necrosis and when was it recovered:
Expand to all the drugs that have ingredients of diazepam:
- Necrosis and drugs with ingredients of diazepam (86 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Valium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Necrosis:
- Necrosis (745 drugs)
Browse all the conditions that are associated with Necrosis:
- Necrosis (970 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on diazepam (the active ingredients of Valium) and Valium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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