Valproic acid and Blood chloride decreased - a phase IV clinical study of FDA data

Summary:

Blood chloride decreased is reported as a side effect among people who take Valproic acid (valproic acid), especially for people who are male, 40-49 old, also take Vitamin D, and have Bipolar i disorder.

The phase IV clinical study analyzes which people have Blood chloride decreased when taking Valproic acid. It is created by eHealthMe based on reports of 35,830 people who have side effects when taking Valproic acid from the FDA, and is updated regularly.

What is Valproic acid?

Valproic acid has active ingredients of valproic acid. It is often used in epilepsy. eHealthMe is studying from 36,193 Valproic acid users. Check the latest studies of Valproic acid.

What is Blood chloride decreased?

Blood chloride decreased is found to be associated with 642 drugs and 756 conditions by eHealthMe. Check the latest studies of Blood chloride decreased.

On Jul, 15, 2026

35,830 people reported to have side effects when taking Valproic acid.
Among them, 20 people (0.06%) have Blood chloride decreased.

Could Valproic acid cause Blood chloride decreased?

Among these 20 people:

What is the gender of people who have Blood chloride decreased when taking Valproic acid? *

female: 47.06 %
male: 52.94 %

What is the age of people who have Blood chloride decreased when taking Valproic acid? *

What are other drugs people take besides Valproic acid? *

What are other side effects people have besides Blood chloride decreased? *

Blood Glucose Increased: 9 people, 45.00%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 9 people, 45.00%
Inappropriate Antidiuretic Hormone Secretion: 7 people, 35.00%
Fever: 7 people, 35.00%
Electrolyte Imbalance: 7 people, 35.00%
Blood Urea Decreased: 6 people, 30.00%
White Blood Cell Count Decreased: 6 people, 30.00%
Blood Albumin Decreased: 6 people, 30.00%
Thrombocytopenia (decrease of platelets in blood): 5 people, 25.00%
Blood Bicarbonate Increased: 5 people, 25.00%

What are the existing conditions these people have? *

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 35.00%
High Blood Pressure: 7 people, 35.00%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 7 people, 35.00%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 5 people, 25.00%
Psychotic Disorder: 3 people, 15.00%
Affective Disorder (mental disorder): 3 people, 15.00%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 2 people, 10.00%
Type 2 Diabetes: 1 person, 5.00%
Anaemia (lack of blood): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Valproic acid and have Blood chloride decreased?

- Check whether Blood chloride decreased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Valproic acid:

Valproic acid (36,193 reports)

Browse all side effects of Valproic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Blood chloride decreased:

Blood chloride decreased (642 drugs)

Browse all the conditions that are associated with Blood chloride decreased:

Blood chloride decreased (756 conditions)

Related publications that referenced our studies

Gupta E, Kunjal R, Cury JD, "Severe hyponatremia due to valproic acid toxicity", Journal of clinical medicine research, 2015 Jan .
Hwabejire JO, Lu J, Liu B, Li Y, Halaweish I, Alam HB, "Valproic acid for the treatment of hemorrhagic shock: a dose-optimization study", journal of surgical research, 2014 Jan .
Gupta E, Kunjal R, Cury JD, "Severe hyponatremia due to valproic acid toxicity", Journal of clinical medicine research, 2015 Jan .
Hwabejire JO, Lu J, Liu B, Li Y, Halaweish I, Alam HB, "Valproic acid for the treatment of hemorrhagic shock: a dose-optimization study", journal of surgical research, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on valproic acid (the active ingredients of Valproic acid) and Valproic acid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.