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Valproic acid and Unilateral hydronephrosis - a phase IV clinical study of FDA data

Summary:

Unilateral hydronephrosis is reported as a side effect among people who take Valproic acid (valproic acid), especially for people who are male, 10-19 old, have been taking the drug for 6 - 12 months also take Carbamazepine, and have Lung cancer - non-small cell.

The phase IV clinical study analyzes which people have Unilateral hydronephrosis when taking Valproic acid. It is created by eHealthMe based on reports of 35,830 people who have side effects when taking Valproic acid from the FDA, and is updated regularly.

What is Valproic acid?

Valproic acid has active ingredients of valproic acid. It is often used in epilepsy. eHealthMe is studying from 36,193 Valproic acid users. Check the latest studies of Valproic acid.

What is Unilateral hydronephrosis?

Unilateral hydronephrosis (kidney stone that causes obstruction of the ureter) is found to be associated with 1,010 drugs and 1,193 conditions by eHealthMe. Check the latest studies of Unilateral hydronephrosis.

On Jul, 16, 2026

35,830 people reported to have side effects when taking Valproic acid.
Among them, 32 people (0.09%) have Unilateral hydronephrosis.

Could Valproic acid cause Unilateral hydronephrosis?

Among these 32 people:

How long have people been on Valproic acid when they have Unilateral hydronephrosis? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Unilateral hydronephrosis when taking Valproic acid? *

  • female: 43.75 %
  • male: 56.25 %

What is the age of people who have Unilateral hydronephrosis when taking Valproic acid? *

  • 0-1: 15.38 %
  • 2-9: 0.0 %
  • 10-19: 38.46 %
  • 20-29: 0.0 %
  • 30-39: 23.08 %
  • 40-49: 15.38 %
  • 50-59: 7.69 %
  • 60+: 0.0 %

What are other drugs people take besides Valproic acid? *

  1. Carbamazepine: 14 people, 43.75%
  2. Lamotrigine: 13 people, 40.62%
  3. Levetiracetam: 13 people, 40.62%
  4. Ethosuximide: 13 people, 40.62%
  5. Vigabatrin: 13 people, 40.62%
  6. Phenytoin: 13 people, 40.62%
  7. Clonazepam: 4 people, 12.50%
  8. Zonisamide: 2 people, 6.25%
  9. Haloperidol: 2 people, 6.25%
  10. Fluoxetine: 2 people, 6.25%

What are other side effects people have besides Unilateral hydronephrosis? *

  1. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle): 14 people, 43.75%
  2. Imperforate Anus (congenital defect of the anus; there is partial or complete obstruction of the anal opening): 14 people, 43.75%
  3. Pyloric Stenosis (narrowing of the passage between the stomach and the small intestine): 13 people, 40.62%
  4. Joint Injury: 13 people, 40.62%
  5. Hydrocele: 9 people, 28.12%
  6. Hypospadias (an abnormal condition in males in which the urethra opens on the under surface of the penis): 8 people, 25.00%
  7. Haematuria (presence of blood in urine): 4 people, 12.50%
  8. Calculus Ureteric (stone in ureter): 3 people, 9.38%
  9. Cough: 3 people, 9.38%
  10. Crystalluria (crystals found in the urine): 3 people, 9.38%

What are the existing conditions these people have? *

  1. Lung Cancer - Non-Small Cell (lung cancer): 2 people, 6.25%
  2. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 3.12%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 3.12%
  4. Muscle Spasms (muscle contraction): 1 person, 3.12%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 3.12%
  6. Metastases To Bone (cancer spreads to bone): 1 person, 3.12%
  7. Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 1 person, 3.12%
  8. Drug Exposure During Pregnancy: 1 person, 3.12%
  9. Constipation: 1 person, 3.12%
  10. Breast Cancer Metastatic: 1 person, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Valproic acid and have Unilateral hydronephrosis?

- Check whether Unilateral hydronephrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Valproic acid:

Unilateral hydronephrosis treatments and more:

How severe was Unilateral hydronephrosis and when was it recovered:

Expand to all the drugs that have ingredients of valproic acid:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Valproic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Unilateral hydronephrosis:

Browse all the conditions that are associated with Unilateral hydronephrosis:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on valproic acid (the active ingredients of Valproic acid) and Valproic acid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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