Valtrex and Paleness - a phase IV clinical study of FDA data

Summary:

Paleness is reported as a side effect among people who take Valtrex (valacyclovir hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Ambien, and have Crohn's disease.

The phase IV clinical study analyzes which people have Paleness when taking Valtrex. It is created by eHealthMe based on reports of 38,014 people who have side effects when taking Valtrex from the FDA, and is updated regularly.

What is Valtrex?

Valtrex has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 40,000 Valtrex users. Check the latest studies of Valtrex.

What is Paleness?

Paleness (unusual lightness of skin colour) is found to be associated with 1,552 drugs and 2,119 conditions by eHealthMe. Check the latest studies of Paleness.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Jul, 30, 2026

38,014 people reported to have side effects when taking Valtrex.
Among them, 60 people (0.16%) have Paleness.

Could Valtrex cause Paleness?

Among these 60 people:

How long have people been on Valtrex when they have Paleness? *

  • < 1 month: 91.67 %
  • 1 - 6 months: 8.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Paleness when taking Valtrex? *

  • female: 68.33 %
  • male: 31.67 %

What is the age of people who have Paleness when taking Valtrex? *

  • 0-1: 0.0 %
  • 2-9: 2.22 %
  • 10-19: 4.44 %
  • 20-29: 8.89 %
  • 30-39: 4.44 %
  • 40-49: 28.89 %
  • 50-59: 22.22 %
  • 60+: 28.89 %

What are other drugs people take besides Valtrex? *

  1. Pantoprazole: 9 people, 15.00%
  2. Ambien: 9 people, 15.00%
  3. Zopiclone: 7 people, 11.67%
  4. Diflucan: 6 people, 10.00%
  5. Prednisone: 5 people, 8.33%
  6. Lexapro: 5 people, 8.33%
  7. Zometa: 5 people, 8.33%
  8. Cyclophosphamide: 4 people, 6.67%
  9. Decadron: 4 people, 6.67%
  10. Protonix: 4 people, 6.67%

What are other side effects people have besides Paleness? *

  1. Weakness: 25 people, 41.67%
  2. Nausea (feeling of having an urge to vomit): 22 people, 36.67%
  3. Dizziness: 21 people, 35.00%
  4. Headache (pain in head): 21 people, 35.00%
  5. Abdominal Pain: 20 people, 33.33%
  6. Stress And Anxiety: 20 people, 33.33%
  7. Nausea And Vomiting: 20 people, 33.33%
  8. Fatigue (feeling of tiredness): 19 people, 31.67%
  9. Fever: 18 people, 30.00%
  10. Anaemia (lack of blood): 18 people, 30.00%

What are the existing conditions these people have? *

  1. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 11 people, 18.33%
  2. Depression: 8 people, 13.33%
  3. Blast Crisis In Myelogenous Leukaemia: 7 people, 11.67%
  4. Asthma: 5 people, 8.33%
  5. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 4 people, 6.67%
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 6.67%
  7. High Blood Pressure: 3 people, 5.00%
  8. Multiple Myeloma (cancer of the plasma cells): 3 people, 5.00%
  9. Haematopoietic Stem Cell Mobilisation: 2 people, 3.33%
  10. Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 2 people, 3.33%

* Approximation only. Some reports may have incomplete information.

Do you take Valtrex and have Paleness?

- Check whether Paleness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Valtrex:

Paleness treatments and more:

How severe was Paleness and when was it recovered:

Expand to all the drugs that have ingredients of valacyclovir hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Valtrex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Paleness:

Browse all the conditions that are associated with Paleness:


How the study uses the data?

The study uses data from the FDA. It is based on valacyclovir hydrochloride (the active ingredients of Valtrex) and Valtrex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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