Valtrex and Retinal detachment - a phase IV clinical study of FDA data

Summary:

Retinal detachment is reported as a side effect among people who take Valtrex (valacyclovir hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Allopurinol, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Retinal detachment when taking Valtrex. It is created by eHealthMe based on reports of 38,014 people who have side effects when taking Valtrex from the FDA, and is updated regularly.

What is Valtrex?

Valtrex has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 39,999 Valtrex users. Check the latest studies of Valtrex.

What is Retinal detachment?

Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue) is found to be associated with 714 drugs and 1,007 conditions by eHealthMe. Check the latest studies of Retinal detachment.

On Aug, 09, 2026

38,014 people reported to have side effects when taking Valtrex.
Among them, 54 people (0.14%) have Retinal detachment.

Among these 54 people:

How long have people been on Valtrex when they have Retinal detachment? *

What is the gender of people who have Retinal detachment when taking Valtrex? *

female: 34 %
male: 66 %

What is the age of people who have Retinal detachment when taking Valtrex? *

What are other drugs people take besides Valtrex? *

What are other side effects people have besides Retinal detachment? *

Joint Pain: 32 people, 59.26%
Fatigue (feeling of tiredness): 31 people, 57.41%
Dyspnea (difficult or laboured breathing): 29 people, 53.70%
High Blood Pressure: 26 people, 48.15%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 22 people, 40.74%
Visual Acuity Reduced (reduced clearness of vision): 20 people, 37.04%
Eye Pain: 19 people, 35.19%
Constipation: 18 people, 33.33%
Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 18 people, 33.33%
Anaemia (lack of blood): 18 people, 33.33%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 22 people, 40.74%
High Blood Pressure: 18 people, 33.33%
Joint Pain: 17 people, 31.48%
Seborrhoeic Dermatitis (a common, inflammatory skin condition that causes flaky, white to yellowish scales to form on oily areas such as the scalp): 17 people, 31.48%
Seasonal Allergy (allergic condition due to certain season): 17 people, 31.48%
Blood Triglycerides Decreased: 17 people, 31.48%
Diarrhea: 17 people, 31.48%
Fluid Retention (an abnormal accumulation of fluid in the blood): 17 people, 31.48%
High Blood Cholesterol: 17 people, 31.48%
Mood Swings (an extreme or rapid change in mood): 17 people, 31.48%

* Approximation only. Some reports may have incomplete information.

Do you take Valtrex and have Retinal detachment?

- Check whether Retinal detachment is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Valtrex:

Valtrex (39,999 reports)

Browse all side effects of Valtrex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Retinal detachment:

Retinal detachment (714 drugs)

Browse all the conditions that are associated with Retinal detachment:

Retinal detachment (1,007 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on valacyclovir hydrochloride (the active ingredients of Valtrex) and Valtrex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.