Venclexta and Restless leg syndrome - a phase IV clinical study of FDA data

Summary:

Restless leg syndrome is reported as a side effect among people who take Venclexta (venetoclax), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Tylenol, and have Chronic lymphocytic leukaemia.

The phase IV clinical study analyzes which people have Restless leg syndrome when taking Venclexta. It is created by eHealthMe based on reports of 31,417 people who have side effects when taking Venclexta from the FDA, and is updated regularly.

What is Venclexta?

Venclexta has active ingredients of venetoclax. eHealthMe is studying from 31,425 Venclexta users. Check the latest studies of Venclexta.

What is Restless leg syndrome?

Restless leg syndrome (a powerful urge to move your legs) is found to be associated with 1,243 drugs and 1,936 conditions by eHealthMe. Check the latest studies of Restless leg syndrome.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

31,417 people reported to have side effects when taking Venclexta.
Among them, 15 people (0.05%) have Restless leg syndrome.

Could Venclexta cause Restless leg syndrome?

Among these 15 people:

How long have people been on Venclexta when they have Restless leg syndrome? *

What is the gender of people who have Restless leg syndrome when taking Venclexta? *

female: 53.33 %
male: 46.67 %

What is the age of people who have Restless leg syndrome when taking Venclexta? *

What are other drugs people take besides Venclexta? *

What are other side effects people have besides Restless leg syndrome? *

Dizziness: 7 people, 46.67%
Abdominal Pain Upper: 6 people, 40.00%
Hypotension (abnormally low blood pressure): 6 people, 40.00%
White Blood Cell Count Decreased: 6 people, 40.00%
Fall: 5 people, 33.33%
Hearing Loss: 5 people, 33.33%
Memory Loss: 5 people, 33.33%
High Blood Pressure: 5 people, 33.33%
Hypersensitivity: 5 people, 33.33%
Urinary Tract Infection: 5 people, 33.33%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 6 people, 40.00%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 6 people, 40.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 33.33%
Spinal Pain (pain in spine): 5 people, 33.33%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 5 people, 33.33%
Nausea And Vomiting: 5 people, 33.33%
Nausea (feeling of having an urge to vomit): 5 people, 33.33%
Dizziness: 5 people, 33.33%
Headache (pain in head): 4 people, 26.67%
Urinary Tract Infection: 4 people, 26.67%

* Approximation only. Some reports may have incomplete information.

Do you take Venclexta and have Restless leg syndrome?

- Check whether Restless leg syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Venclexta:

Venclexta (31,425 reports)

Browse all side effects of Venclexta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Restless leg syndrome:

Restless leg syndrome (1,243 drugs)

Browse all the conditions that are associated with Restless leg syndrome:

Restless leg syndrome (1,936 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on venetoclax (the active ingredients of Venclexta) and Venclexta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.