Venlafaxine hydrochloride and Skin atrophy - a phase IV clinical study of FDA data

Summary:

Skin atrophy is reported as a side effect among people who take Venlafaxine hydrochloride (venlafaxine hydrochloride), especially for people who are female, 50-59 old, also take Lyrica, and have Complex regional pain syndrome.

The phase IV clinical study analyzes which people have Skin atrophy when taking Venlafaxine hydrochloride. It is created by eHealthMe based on reports of 15,424 people who have side effects when taking Venlafaxine hydrochloride from the FDA, and is updated regularly.

What is Venlafaxine hydrochloride?

Venlafaxine hydrochloride has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 17,916 Venlafaxine hydrochloride users. Check the latest studies of Venlafaxine hydrochloride.

What is Skin atrophy?

Skin atrophy (wasting of skin) is found to be associated with 622 drugs and 718 conditions by eHealthMe. Check the latest studies of Skin atrophy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

15,424 people reported to have side effects when taking Venlafaxine hydrochloride.
Among them, 11 people (0.07%) have Skin atrophy.

Could Venlafaxine hydrochloride cause Skin atrophy?

Among these 11 people:

What is the gender of people who have Skin atrophy when taking Venlafaxine hydrochloride? *

female: 70 %
male: 30 %

What is the age of people who have Skin atrophy when taking Venlafaxine hydrochloride? *

What are other drugs people take besides Venlafaxine hydrochloride? *

Trental: 7 people, 63.64%
Lyrica: 7 people, 63.64%
Deflazacort: 6 people, 54.55%
Ibuprofen: 6 people, 54.55%
Phenytoin: 5 people, 45.45%
Buprenorphine: 5 people, 45.45%
Clonazepam: 5 people, 45.45%
Diazepam: 5 people, 45.45%
Trazodone Hydrochloride: 5 people, 45.45%
Acetaminophen: 5 people, 45.45%

What are other side effects people have besides Skin atrophy? *

Suicidal Ideation: 9 people, 81.82%
Pain: 8 people, 72.73%
Peripheral Coldness: 8 people, 72.73%
Diarrhea: 7 people, 63.64%
Hyperhidrosis (abnormally increased sweating): 7 people, 63.64%
Hypokinesia (decreased bodily movement): 7 people, 63.64%
Hypotonia (low muscle tone): 7 people, 63.64%
Joint Contracture (a permanent shortening of a muscle or joint): 7 people, 63.64%
Fever: 7 people, 63.64%
Nausea (feeling of having an urge to vomit): 7 people, 63.64%

What are the existing conditions these people have? *

Complex Regional Pain Syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet)): 7 people, 63.64%
Sleep Disorder: 3 people, 27.27%
Skin Disorder (skin disease): 3 people, 27.27%
Androgenetic Alopecia (common form of hair loss): 2 people, 18.18%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 9.09%
Quit Smoking: 1 person, 9.09%
Pain: 1 person, 9.09%
Osteoporosis (bones weak and more likely to break): 1 person, 9.09%
Nephrotic Syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema): 1 person, 9.09%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Venlafaxine hydrochloride and have Skin atrophy?

- Check whether Skin atrophy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Venlafaxine hydrochloride:

Venlafaxine hydrochloride (17,916 reports)

Skin atrophy treatments and more:

Skin atrophy (6,670 reports)

Browse all side effects of Venlafaxine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Skin atrophy:

Skin atrophy (622 drugs)

Browse all the conditions that are associated with Skin atrophy:

Skin atrophy (718 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on venlafaxine hydrochloride (the active ingredients of Venlafaxine hydrochloride) and Venlafaxine hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.