Vesicare and International normalised ratio increased - a phase IV clinical study of FDA data

Summary:

International normalised ratio increased is reported as a side effect among people who take Vesicare (solifenacin succinate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Coumadin, and have Pain.

The phase IV clinical study analyzes which people have International normalised ratio increased when taking Vesicare. It is created by eHealthMe based on reports of 29,875 people who have side effects when taking Vesicare from the FDA, and is updated regularly.

What is Vesicare?

Vesicare has active ingredients of solifenacin succinate. It is often used in urge incontinence. eHealthMe is studying from 30,655 Vesicare users. Check the latest studies of Vesicare.

What is International normalised ratio increased?

International normalised ratio increased is found to be associated with 1,333 drugs and 1,727 conditions by eHealthMe. Check the latest studies of International normalised ratio increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

29,875 people reported to have side effects when taking Vesicare.
Among them, 51 people (0.17%) have International normalised ratio increased.

Could Vesicare cause International normalised ratio increased?

Among these 51 people:

How long have people been on Vesicare when they have International normalised ratio increased? *

What is the gender of people who have International normalised ratio increased when taking Vesicare? *

female: 59.18 %
male: 40.82 %

What is the age of people who have International normalised ratio increased when taking Vesicare? *

What are other drugs people take besides Vesicare? *

What are other side effects people have besides International normalised ratio increased? *

Weakness: 6 people, 11.76%
Fall: 5 people, 9.80%
Headache (pain in head): 5 people, 9.80%
Blood Glucose Increased: 4 people, 7.84%
High Blood Pressure: 4 people, 7.84%
Dizziness: 4 people, 7.84%
Confusional State: 4 people, 7.84%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 4 people, 7.84%
Anaemia (lack of blood): 4 people, 7.84%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 7.84%

What are the existing conditions these people have? *

Pain: 8 people, 15.69%
High Blood Pressure: 7 people, 13.73%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 6 people, 11.76%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 11.76%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 7.84%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 5.88%
Multiple Myeloma (cancer of the plasma cells): 3 people, 5.88%
Gastric Ulcer (stomach ulcer): 3 people, 5.88%
Dementia (madness): 3 people, 5.88%
High Blood Cholesterol: 3 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Vesicare and have International normalised ratio increased?

- Check whether International normalised ratio increased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vesicare:

Vesicare (30,655 reports)

International normalised ratio increased treatments and more:

International normalised ratio increased (40,071 reports)

How severe was International normalised ratio increased and when was it recovered:

International normalised ratio increased in Vesicare

Expand to all the drugs that have ingredients of solifenacin succinate:

International normalised ratio increased and drugs with ingredients of solifenacin succinate (102 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vesicare:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with International normalised ratio increased:

International normalised ratio increased (1,333 drugs)

Browse all the conditions that are associated with International normalised ratio increased:

International normalised ratio increased (1,727 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on solifenacin succinate (the active ingredients of Vesicare) and Vesicare (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.