Vfend and Toxic skin eruption - a phase IV clinical study of FDA data

Summary:

Toxic skin eruption is reported as a side effect among people who take Vfend (voriconazole), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Nexium, and have Bronchopulmonary aspergillosis.

The phase IV clinical study analyzes which people have Toxic skin eruption when taking Vfend. It is created by eHealthMe based on reports of 12,081 people who have side effects when taking Vfend from the FDA, and is updated regularly.

What is Vfend?

Vfend has active ingredients of voriconazole. It is often used in aspergillosis. eHealthMe is studying from 12,128 Vfend users. Check the latest studies of Vfend.

What is Toxic skin eruption?

Toxic skin eruption (skin breakdown due to toxic substance) is found to be associated with 638 drugs and 1,064 conditions by eHealthMe. Check the latest studies of Toxic skin eruption.

On Jul, 15, 2026

12,081 people reported to have side effects when taking Vfend.
Among them, 46 people (0.38%) have Toxic skin eruption.

Among these 46 people:

How long have people been on Vfend when they have Toxic skin eruption? *

What is the gender of people who have Toxic skin eruption when taking Vfend? *

female: 32.61 %
male: 67.39 %

What is the age of people who have Toxic skin eruption when taking Vfend? *

What are other drugs people take besides Vfend? *

What are other side effects people have besides Toxic skin eruption? *

Fever: 8 people, 17.39%
Rashes (redness): 7 people, 15.22%
Lung Disorder (lung disease): 7 people, 15.22%
Rash Maculo-Papular (red area on the skin that is covered with small confluent bumps): 6 people, 13.04%
Erythema Multiforme (a type of hypersensitivity reaction): 6 people, 13.04%
Acute Kidney Failure: 5 people, 10.87%
C-Reactive Protein Increased: 4 people, 8.70%
Lymphopenia (an abnormally low level of lymphocytes in the blood): 4 people, 8.70%
Nodule (a growth of abnormal tissue): 3 people, 6.52%
Pityriasis (a skin disease characterized by the shedding of fine flaky scales): 3 people, 6.52%

What are the existing conditions these people have? *

Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 7 people, 15.22%
Pain: 6 people, 13.04%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 8.70%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.52%
Neoplasm Malignant (cancer tumour): 3 people, 6.52%
High Blood Pressure: 3 people, 6.52%
Febrile Bone Marrow Aplasia (bone marrow greatly decreases or stops production of blood cells): 2 people, 4.35%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 4.35%
Lung Adenocarcinoma Metastatic (a form of non-small cell lung cancer spreads to other part): 2 people, 4.35%
Bacterial Infection: 2 people, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Vfend and have Toxic skin eruption?

- Check whether Toxic skin eruption is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vfend:

Vfend (12,128 reports)

Browse all side effects of Vfend:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Toxic skin eruption:

Toxic skin eruption (638 drugs)

Browse all the conditions that are associated with Toxic skin eruption:

Toxic skin eruption (1,064 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on voriconazole (the active ingredients of Vfend) and Vfend (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.