Adderall and Rapamune drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) and Rapamune (sirolimus). Common drug interactions include malaise among females and spinal compression fracture among males.

The phase IV clinical study analyzes what interactions people have when they take Adderall and Rapamune. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,224 Adderall users. Check the latest studies of Adderall.

What is Rapamune?

Rapamune has active ingredients of sirolimus. It is often used in kidney transplant. eHealthMe is studying from 13,848 Rapamune users. Check the latest studies of Rapamune.

On Jul, 15, 2026

11 people who take Adderall and Rapamune together, and have interactions are studied.

Adderall and Rapamune drug interactions.

What are the common drug interactions of Adderall and Rapamune, by gender? *:

female:

Malaise (a feeling of general discomfort or uneasiness)
Secretion discharge
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Pulmonary mycosis (lung infection caused by yeast-like fungi)
Renal failure (kidney dysfunction)
Blood glucose increased
Blood magnesium decreased
Dehydration (dryness resulting from the removal of water)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hypotension (abnormally low blood pressure)

male:

Spinal compression fracture (fracture due to spinal compression on bone)
Anger
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Growth retardation (delayed growth)
Hyperplasia (enlargement of an organ or tissue)
Inflammation
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)

What are the common drug interactions of Adderall and Rapamune, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Hyperplasia (enlargement of an organ or tissue)
Inflammation
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)

10-19:

Spinal compression fracture (fracture due to spinal compression on bone)

20-29:

Hypotension (abnormally low blood pressure)
Renal failure (kidney dysfunction)
Renal pain (kidney pain)
Urine amphetamine positive
Urine cannabinoids increased
Blood glucose increased
Blood magnesium decreased
Dehydration (dryness resulting from the removal of water)
Drug screen positive

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Abdominal discomfort
Dysphonia (speech disorder attributable to a disorder of phonation)
Malaise (a feeling of general discomfort or uneasiness)
Secretion discharge
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Pulmonary mycosis (lung infection caused by yeast-like fungi)

What are the existing conditions these people have? *

Hypotension (abnormally low blood pressure): 5 people, 45.45%
Type 1 Diabetes: 3 people, 27.27%
High Blood Cholesterol: 3 people, 27.27%
High Blood Pressure: 3 people, 27.27%
Pain: 3 people, 27.27%
Abdominal Pain Upper: 3 people, 27.27%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 18.18%
Respiratory Disorder (respiratory disease): 2 people, 18.18%
Gout (uric acid crystals building up in the body): 2 people, 18.18%
Diabetes Insipidus (diabetes caused by a deficiency of the pituitary hormone vasopressin, which regulates kidney function): 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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