Vicodin and Activated partial thromboplastin time prolonged - a phase IV clinical study of FDA data

Summary:

Activated partial thromboplastin time prolonged is reported as a side effect among people who take Vicodin (acetaminophen; hydrocodone bitartrate), especially for people who are male, 60+ old, also take Vioxx, and have Metastatic renal cell carcinoma.

The phase IV clinical study analyzes which people have Activated partial thromboplastin time prolonged when taking Vicodin. It is created by eHealthMe based on reports of 59,416 people who have side effects when taking Vicodin from the FDA, and is updated regularly.

What is Vicodin?

Vicodin has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 63,357 Vicodin users. Check the latest studies of Vicodin.

What is Activated partial thromboplastin time prolonged?

Activated partial thromboplastin time prolonged is found to be associated with 761 drugs and 1,209 conditions by eHealthMe. Check the latest studies of Activated partial thromboplastin time prolonged.

On Jul, 17, 2026

59,416 people reported to have side effects when taking Vicodin.
Among them, 87 people (0.15%) have Activated partial thromboplastin time prolonged.

Could Vicodin cause Activated partial thromboplastin time prolonged?

Among these 87 people:

What is the gender of people who have Activated partial thromboplastin time prolonged when taking Vicodin? *

female: 44.71 %
male: 55.29 %

What is the age of people who have Activated partial thromboplastin time prolonged when taking Vicodin? *

What are other drugs people take besides Vicodin? *

What are other side effects people have besides Activated partial thromboplastin time prolonged? *

Headache (pain in head): 22 people, 25.29%
International Normalised Ratio Increased: 21 people, 24.14%
Dyspnea (difficult or laboured breathing): 20 people, 22.99%
Stress And Anxiety: 19 people, 21.84%
Chest Pain: 19 people, 21.84%
Oedema Peripheral (superficial swelling): 19 people, 21.84%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 18 people, 20.69%
Cardiac Failure Congestive: 18 people, 20.69%
Bradycardia (abnormally slow heart action): 17 people, 19.54%
Hypotension (abnormally low blood pressure): 17 people, 19.54%

What are the existing conditions these people have? *

Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 5 people, 5.75%
Chest Pain: 4 people, 4.60%
Osteoporosis (bones weak and more likely to break): 3 people, 3.45%
Multiple Myeloma (cancer of the plasma cells): 3 people, 3.45%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 3.45%
Pulmonary Embolism (blockage of the main artery of the lung): 3 people, 3.45%
Dyspnea (difficult or laboured breathing): 2 people, 2.30%
Lung Cancer - Non-Small Cell (lung cancer): 2 people, 2.30%
Depression: 2 people, 2.30%
High Blood Cholesterol: 2 people, 2.30%

* Approximation only. Some reports may have incomplete information.

Do you take Vicodin and have Activated partial thromboplastin time prolonged?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vicodin:

Vicodin (63,357 reports)

Activated partial thromboplastin time prolonged treatments and more:

Activated partial thromboplastin time prolonged (8,799 reports)

How severe was Activated partial thromboplastin time prolonged and when was it recovered:

Activated partial thromboplastin time prolonged in Vicodin

Expand to all the drugs that have ingredients of acetaminophen; hydrocodone bitartrate:

Activated partial thromboplastin time prolonged and drugs with ingredients of acetaminophen; hydrocodone bitartrate (163 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vicodin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Activated partial thromboplastin time prolonged:

Activated partial thromboplastin time prolonged (761 drugs)

Browse all the conditions that are associated with Activated partial thromboplastin time prolonged:

Activated partial thromboplastin time prolonged (1,209 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; hydrocodone bitartrate (the active ingredients of Vicodin) and Vicodin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.