1. Home
  2. Analysis
  3. Viibryd
  4. Osteoporosis

Viibryd and Osteoporosis - a phase IV clinical study of FDA data

Summary:

Osteoporosis is reported as a side effect among people who take Viibryd (vilazodone hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for 2 - 5 years also take Nuvigil, and have Hiv infection.

The phase IV clinical study analyzes which people have Osteoporosis when taking Viibryd. It is created by eHealthMe based on reports of 10,186 people who have side effects when taking Viibryd from the FDA, and is updated regularly.

What is Viibryd?

Viibryd has active ingredients of vilazodone hydrochloride. It is often used in depression. eHealthMe is studying from 11,106 Viibryd users. Check the latest studies of Viibryd.

What is Osteoporosis?

Osteoporosis (bones weak and more likely to break) is found to be associated with 1,814 drugs and 1,900 conditions by eHealthMe. Check the latest studies of Osteoporosis.

On Jul, 04, 2026

10,186 people reported to have side effects when taking Viibryd.
Among them, 31 people (0.3%) have Osteoporosis.

Could Viibryd cause Osteoporosis?

Among these 31 people:

How long have people been on Viibryd when they have Osteoporosis? *

  • < 1 month: 28.57 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 71.43 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Osteoporosis when taking Viibryd? *

  • female: 72.41 %
  • male: 27.59 %

What is the age of people who have Osteoporosis when taking Viibryd? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 21.05 %
  • 50-59: 47.37 %
  • 60+: 31.58 %

What are other drugs people take besides Viibryd? *

  1. Synthroid: 10 people, 32.26%
  2. Nuvigil: 10 people, 32.26%
  3. Pantoprazole: 9 people, 29.03%
  4. Fish Oil: 8 people, 25.81%
  5. Abilify: 8 people, 25.81%
  6. Escitalopram: 7 people, 22.58%
  7. Diphenoxylate Hydrochloride And Atropine Sulfate: 7 people, 22.58%
  8. Flonase Allergy Relief: 7 people, 22.58%
  9. Atripla: 7 people, 22.58%
  10. Xyrem: 7 people, 22.58%

What are other side effects people have besides Osteoporosis? *

  1. Pain: 14 people, 45.16%
  2. Emotional Distress: 11 people, 35.48%
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable): 9 people, 29.03%
  4. Bone Density Decreased: 9 people, 29.03%
  5. Chronic Kidney Disease: 7 people, 22.58%
  6. Back Pain: 6 people, 19.35%
  7. Foot Fracture: 5 people, 16.13%
  8. Pneumonia: 5 people, 16.13%
  9. Neck Pain: 5 people, 16.13%
  10. Fatigue (feeling of tiredness): 4 people, 12.90%

What are the existing conditions these people have? *

  1. Hiv Infection: 11 people, 35.48%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 22.58%
  3. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 22.58%
  4. Immunodeficiency Common Variable: 5 people, 16.13%
  5. High Blood Cholesterol: 5 people, 16.13%
  6. Pain: 4 people, 12.90%
  7. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 12.90%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 12.90%
  9. Tension Headache: 3 people, 9.68%
  10. High Blood Pressure: 3 people, 9.68%

* Approximation only. Some reports may have incomplete information.

Do you take Viibryd and have Osteoporosis?

- Check whether Osteoporosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Viibryd:

Osteoporosis treatments and more:

How severe was Osteoporosis and when was it recovered:

Expand to all the drugs that have ingredients of vilazodone hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Viibryd:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Osteoporosis:

Browse all the conditions that are associated with Osteoporosis:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on vilazodone hydrochloride (the active ingredients of Viibryd) and Viibryd (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2026 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.