Vimpat and Blood creatine phosphokinase increased - a phase IV clinical study of FDA data

Summary:

Blood creatine phosphokinase increased is reported as a side effect among people who take Vimpat (lacosamide), especially for people who are female, 20-29 old, have been taking the drug for < 1 month also take Keppra, and have Status epilepticus.

The phase IV clinical study analyzes which people have Blood creatine phosphokinase increased when taking Vimpat. It is created by eHealthMe based on reports of 20,279 people who have side effects when taking Vimpat from the FDA, and is updated regularly.

What is Vimpat?

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,832 Vimpat users. Check the latest studies of Vimpat.

What is Blood creatine phosphokinase increased?

Blood creatine phosphokinase increased is found to be associated with 1,497 drugs and 2,095 conditions by eHealthMe. Check the latest studies of Blood creatine phosphokinase increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

20,279 people reported to have side effects when taking Vimpat.
Among them, 88 people (0.43%) have Blood creatine phosphokinase increased.

Could Vimpat cause Blood creatine phosphokinase increased?

Among these 88 people:

How long have people been on Vimpat when they have Blood creatine phosphokinase increased? *

What is the gender of people who have Blood creatine phosphokinase increased when taking Vimpat? *

female: 83.95 %
male: 16.05 %

What is the age of people who have Blood creatine phosphokinase increased when taking Vimpat? *

What are other drugs people take besides Vimpat? *

Keppra: 60 people, 68.18%
Forane: 43 people, 48.86%
Magnesium: 41 people, 46.59%
Midazolam: 39 people, 44.32%
Clobazam: 36 people, 40.91%
Topiramate: 25 people, 28.41%
Dexamethasone: 22 people, 25.00%
Ketamine Hydrochloride: 22 people, 25.00%
Propofol: 22 people, 25.00%
Valproic Acid: 22 people, 25.00%

What are other side effects people have besides Blood creatine phosphokinase increased? *

Arrhythmias (irregular heartbeat): 58 people, 65.91%
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin): 58 people, 65.91%
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 58 people, 65.91%
Propofol Infusion Syndrome: 58 people, 65.91%
Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 57 people, 64.77%
Blood Gases Abnormal: 47 people, 53.41%
Electrocardiogram Qt Prolonged: 47 people, 53.41%
Blood Lactic Acid Increased: 47 people, 53.41%
Drug Ineffective: 25 people, 28.41%
Partial Seizures (seizures which affect only a part of the brain at onset): 22 people, 25.00%

What are the existing conditions these people have? *

Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 61 people, 69.32%
Malignant Melanoma (skin cancer rises from melancytes): 6 people, 6.82%
Type 2 Diabetes: 3 people, 3.41%
High Blood Pressure: 3 people, 3.41%
Sedation: 3 people, 3.41%
Lung Neoplasm Malignant (cancer tumour of lung): 3 people, 3.41%
Pain: 2 people, 2.27%
Rasmussen Encephalitis (a rare inflammatory neurological disease, characterized by frequent and severe seizures, loss of motor skills and speech): 2 people, 2.27%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 1.14%
Cardiac Failure: 1 person, 1.14%

* Approximation only. Some reports may have incomplete information.

Do you take Vimpat and have Blood creatine phosphokinase increased?

- Check whether Blood creatine phosphokinase increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vimpat:

Vimpat (20,832 reports)

Blood creatine phosphokinase increased treatments and more:

Blood creatine phosphokinase increased (46,724 reports)

How severe was Blood creatine phosphokinase increased and when was it recovered:

Blood creatine phosphokinase increased in Vimpat

Expand to all the drugs that have ingredients of lacosamide:

Blood creatine phosphokinase increased and drugs with ingredients of lacosamide (127 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vimpat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Blood creatine phosphokinase increased:

Blood creatine phosphokinase increased (1,497 drugs)

Browse all the conditions that are associated with Blood creatine phosphokinase increased:

Blood creatine phosphokinase increased (2,095 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lacosamide (the active ingredients of Vimpat) and Vimpat (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.