Viramune and Splenomegaly - a phase IV clinical study of FDA data

Summary:

Splenomegaly is reported as a side effect among people who take Viramune (nevirapine), especially for people who are male, 0-1 old, have been taking the drug for < 1 month also take Retrovir, and have Acquired immunodeficiency syndrome.

The phase IV clinical study analyzes which people have Splenomegaly when taking Viramune. It is created by eHealthMe based on reports of 11,323 people who have side effects when taking Viramune from the FDA, and is updated regularly.

What is Viramune?

Viramune has active ingredients of nevirapine. It is often used in hiv infection. eHealthMe is studying from 11,381 Viramune users. Check the latest studies of Viramune.

What is Splenomegaly?

Splenomegaly (enlargement of spleen) is found to be associated with 1,111 drugs and 1,477 conditions by eHealthMe. Check the latest studies of Splenomegaly.



On Jul, 17, 2026

11,323 people reported to have side effects when taking Viramune.
Among them, 43 people (0.38%) have Splenomegaly.

Could Viramune cause Splenomegaly?

Among these 43 people:

How long have people been on Viramune when they have Splenomegaly? *

  • < 1 month: 33.33 %
  • 1 - 6 months: 25.0 %
  • 6 - 12 months: 25.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 16.67 %
  • 10+ years: 0.0 %

What is the gender of people who have Splenomegaly when taking Viramune? *

  • female: 18.6 %
  • male: 81.4 %

What is the age of people who have Splenomegaly when taking Viramune? *

  • 0-1: 34.38 %
  • 2-9: 12.5 %
  • 10-19: 0.0 %
  • 20-29: 3.12 %
  • 30-39: 21.88 %
  • 40-49: 12.5 %
  • 50-59: 9.38 %
  • 60+: 6.25 %

What are other drugs people take besides Viramune? *

  1. Retrovir: 21 people, 48.84%
  2. Combivir: 17 people, 39.53%
  3. Hivid: 14 people, 32.56%
  4. Haldol: 13 people, 30.23%
  5. Zerit: 9 people, 20.93%
  6. Epivir: 9 people, 20.93%
  7. Videx: 7 people, 16.28%
  8. Didanosine: 7 people, 16.28%
  9. Viracept: 7 people, 16.28%
  10. Crixivan: 6 people, 13.95%

What are other side effects people have besides Splenomegaly? *

  1. Hepatomegaly (abnormal enlargement of the liver): 18 people, 41.86%
  2. Alanine Aminotransferase Increased: 15 people, 34.88%
  3. Fever: 13 people, 30.23%
  4. Neutropenia Neonatal (an abnormally low number of neutrophils in below a month baby): 13 people, 30.23%
  5. Idiopathic Or Primary Livedo Reticularis (netlike pattern of reddish-blue skin discoloration, usually on the legs): 8 people, 18.60%
  6. Tremor Neonatal (excited neuromuscular activity of newborns): 8 people, 18.60%
  7. Blood Lactic Acid Increased: 7 people, 16.28%
  8. Portal Hypertension (increase in the blood pressure within a system of veins called the portal venous system): 7 people, 16.28%
  9. Skin Discoloration: 7 people, 16.28%
  10. Hepatic Failure (liver failure): 7 people, 16.28%

What are the existing conditions these people have? *

  1. Gout (uric acid crystals building up in the body): 1 person, 2.33%
  2. Acquired Immunodeficiency Syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv)): 1 person, 2.33%

* Approximation only. Some reports may have incomplete information.

Do you take Viramune and have Splenomegaly?

- Check whether Splenomegaly is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Viramune:

Splenomegaly treatments and more:

How severe was Splenomegaly and when was it recovered:

Expand to all the drugs that have ingredients of nevirapine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Viramune:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Splenomegaly:

Browse all the conditions that are associated with Splenomegaly:


How the study uses the data?

The study uses data from the FDA. It is based on nevirapine (the active ingredients of Viramune) and Viramune (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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