Vitamin b2 and Poor quality sleep - a phase IV clinical study of FDA data

Summary:

Poor quality sleep is reported as a side effect among people who take Vitamin b2 (riboflavin), especially for people who are female, 50-59 old, also take Cimetidine, and have Complex regional pain syndrome.

The phase IV clinical study analyzes which people have Poor quality sleep when taking Vitamin b2. It is created by eHealthMe based on reports of 1,584 people who have side effects when taking Vitamin b2 from the FDA, and is updated regularly.

What is Vitamin b2?

Vitamin b2 has active ingredients of riboflavin. It is often used in migraine. eHealthMe is studying from 1,740 Vitamin b2 users. Check the latest studies of Vitamin b2.

What is Poor quality sleep?

Poor quality sleep is found to be associated with 1,265 drugs and 1,163 conditions by eHealthMe. Check the latest studies of Poor quality sleep.

On Jul, 08, 2026

1,584 people reported to have side effects when taking Vitamin b2.
Among them, 63 people (3.98%) have Poor quality sleep.

Could Vitamin b2 cause Poor quality sleep?

Among these 63 people:

What is the gender of people who have Poor quality sleep when taking Vitamin b2? *

female: 100 %
male: 0.0 %

What is the age of people who have Poor quality sleep when taking Vitamin b2? *

What are other drugs people take besides Vitamin b2? *

What are other side effects people have besides Poor quality sleep? *

Fatigue (feeling of tiredness): 61 people, 96.83%
Insomnia (sleeplessness): 52 people, 82.54%
Cataract (clouding of the lens inside the eye): 52 people, 82.54%
Oral Herpes (viral infection of mouth): 51 people, 80.95%
Bone Density Decreased: 51 people, 80.95%
Body Tinea (ringworm of the body): 51 people, 80.95%
Infection Susceptibility Increased: 51 people, 80.95%
Purpura (purplish discoloration of the skin): 51 people, 80.95%
Cellulitis (infection under the skin): 51 people, 80.95%
Skin Disorder (skin disease): 51 people, 80.95%

What are the existing conditions these people have? *

Complex Regional Pain Syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet)): 54 people, 85.71%
Hyperlipidaemia (presence of excess lipids in the blood): 40 people, 63.49%
Insomnia (sleeplessness): 40 people, 63.49%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 5 people, 7.94%
Sleep Disorder: 3 people, 4.76%
Nausea (feeling of having an urge to vomit): 2 people, 3.17%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 3.17%
Headache (pain in head): 2 people, 3.17%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 1 person, 1.59%
Muscle Spasms (muscle contraction): 1 person, 1.59%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamin b2 and have Poor quality sleep?

- Check whether Poor quality sleep is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vitamin b2:

Vitamin b2 (1,740 reports)

Browse all side effects of Vitamin b2:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Poor quality sleep:

Poor quality sleep (1,265 drugs)

Browse all the conditions that are associated with Poor quality sleep:

Poor quality sleep (1,163 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on riboflavin (the active ingredients of Vitamin b2) and Vitamin b2 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.