Vitamin b2 and Weakness - a phase IV clinical study of FDA data

Summary:

Weakness is reported as a side effect among people who take Vitamin b2 (riboflavin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Vitamin D3, and have Relapsing-remitting multiple sclerosis.

The phase IV clinical study analyzes which people have Weakness when taking Vitamin b2. It is created by eHealthMe based on reports of 1,584 people who have side effects when taking Vitamin b2 from the FDA, and is updated regularly.

What is Vitamin b2?

Vitamin b2 has active ingredients of riboflavin. It is often used in migraine. eHealthMe is studying from 1,740 Vitamin b2 users. Check the latest studies of Vitamin b2.

What is Weakness?

Weakness is found to be associated with 3,638 drugs and 6,617 conditions by eHealthMe. Check the latest studies of Weakness.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Jul, 16, 2026

1,584 people reported to have side effects when taking Vitamin b2.
Among them, 84 people (5.3%) have Weakness.

Could Vitamin b2 cause Weakness?

Among these 84 people:

How long have people been on Vitamin b2 when they have Weakness? *

  • < 1 month: 33.33 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 33.33 %
  • 2 - 5 years: 33.33 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Weakness when taking Vitamin b2? *

  • female: 82.72 %
  • male: 17.28 %

What is the age of people who have Weakness when taking Vitamin b2? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 3.17 %
  • 30-39: 4.76 %
  • 40-49: 23.81 %
  • 50-59: 20.63 %
  • 60+: 47.62 %

What are other drugs people take besides Vitamin b2? *

  1. Vitamin D3: 29 people, 34.52%
  2. Vitamin B12: 24 people, 28.57%
  3. Magnesium: 18 people, 21.43%
  4. Vitamin C: 14 people, 16.67%
  5. Pantoprazole: 13 people, 15.48%
  6. Ocrevus: 11 people, 13.10%
  7. Vitamin D: 11 people, 13.10%
  8. Benadryl: 10 people, 11.90%
  9. Flexeril: 10 people, 11.90%
  10. Lasix: 10 people, 11.90%

What are other side effects people have besides Weakness? *

  1. Fatigue (feeling of tiredness): 32 people, 38.10%
  2. Headache (pain in head): 22 people, 26.19%
  3. Hypoaesthesia (reduced sense of touch or sensation): 18 people, 21.43%
  4. Dizziness: 16 people, 19.05%
  5. Nausea (feeling of having an urge to vomit): 16 people, 19.05%
  6. Pain In Extremity: 14 people, 16.67%
  7. Muscle Spasms (muscle contraction): 13 people, 15.48%
  8. Fever: 13 people, 15.48%
  9. Memory Loss: 13 people, 15.48%
  10. Cough: 12 people, 14.29%

What are the existing conditions these people have? *

  1. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 12 people, 14.29%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 9 people, 10.71%
  3. Asthma: 6 people, 7.14%
  4. High Blood Pressure: 6 people, 7.14%
  5. Insomnia (sleeplessness): 6 people, 7.14%
  6. Depression: 6 people, 7.14%
  7. Muscle Spasms (muscle contraction): 6 people, 7.14%
  8. Pneumonia: 5 people, 5.95%
  9. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 5.95%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamin b2 and have Weakness?

- Check whether Weakness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vitamin b2:

Weakness treatments and more:

How severe was Weakness and when was it recovered:

Expand to all the drugs that have ingredients of riboflavin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vitamin b2:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Weakness:

Browse all the conditions that are associated with Weakness:


How the study uses the data?

The study uses data from the FDA. It is based on riboflavin (the active ingredients of Vitamin b2) and Vitamin b2 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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