Vitamin c and Intervertebral disc compression - a phase IV clinical study of FDA data

Summary:

Intervertebral disc compression is reported as a side effect among people who take Vitamin c (l-ascorbic acid), especially for people who are female, 60+ old, also take Vitamin D3, and have Immunodeficiency common variable.

The phase IV clinical study analyzes which people have Intervertebral disc compression when taking Vitamin c. It is created by eHealthMe based on reports of 89,802 people who have side effects when taking Vitamin c from the FDA, and is updated regularly.

What is Vitamin c?

Vitamin c has active ingredients of l-ascorbic acid. It is often used in immune response. eHealthMe is studying from 92,472 Vitamin c users. Check the latest studies of Vitamin c.

What is Intervertebral disc compression?

Intervertebral disc compression (spinal disc compression) is found to be associated with 285 drugs and 286 conditions by eHealthMe. Check the latest studies of Intervertebral disc compression.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

89,802 people reported to have side effects when taking Vitamin c.
Among them, 21 people (0.02%) have Intervertebral disc compression.

Could Vitamin c cause Intervertebral disc compression?

Among these 21 people:

What is the gender of people who have Intervertebral disc compression when taking Vitamin c? *

female: 80.95 %
male: 19.05 %

What is the age of people who have Intervertebral disc compression when taking Vitamin c? *

What are other drugs people take besides Vitamin c? *

What are other side effects people have besides Intervertebral disc compression? *

Infusion Site Pain: 11 people, 52.38%
Intervertebral Disc Protrusion (spinal disc protrusion): 11 people, 52.38%
Back Pain: 11 people, 52.38%
Joint Pain: 11 people, 52.38%
Pneumonia: 10 people, 47.62%
Chest Pain: 10 people, 47.62%
Scar: 10 people, 47.62%
Infection: 9 people, 42.86%
Joint Swelling: 9 people, 42.86%
Infusion Site Haemorrhage (bleeding from infusion site): 8 people, 38.10%

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 11 people, 52.38%
Primary Immunodeficiency Syndrome: 6 people, 28.57%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 3 people, 14.29%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 9.52%
Osteoporosis (bones weak and more likely to break): 2 people, 9.52%
Multiple Myeloma (cancer of the plasma cells): 2 people, 9.52%
Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 2 people, 9.52%
Vitamin B12 Deficiency: 1 person, 4.76%
Stress And Anxiety: 1 person, 4.76%
Quit Smoking: 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamin c and have Intervertebral disc compression?

- Check whether Intervertebral disc compression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vitamin c:

Vitamin c (92,472 reports)

Browse all side effects of Vitamin c:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intervertebral disc compression:

Intervertebral disc compression (285 drugs)

Browse all the conditions that are associated with Intervertebral disc compression:

Intervertebral disc compression (286 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on l-ascorbic acid (the active ingredients of Vitamin c) and Vitamin c (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.