Vitamin d3 and Pigmentation disorder - a phase IV clinical study of FDA data

Summary:

Pigmentation disorder is reported as a side effect among people who take Vitamin d3 (cholecalciferol), especially for people who are female, 60+ old, also take Synthroid, and have Polycythaemia vera.

The phase IV clinical study analyzes which people have Pigmentation disorder when taking Vitamin d3. It is created by eHealthMe based on reports of 31,612 people who have side effects when taking Vitamin d3 from the FDA, and is updated regularly.

What is Vitamin d3?

Vitamin d3 has active ingredients of cholecalciferol. It is often used in heart health. eHealthMe is studying from 32,171 Vitamin d3 users. Check the latest studies of Vitamin d3.

What is Pigmentation disorder?

Pigmentation disorder (disturbances of human skin colour) is found to be associated with 642 drugs and 771 conditions by eHealthMe. Check the latest studies of Pigmentation disorder.

On Jul, 09, 2026

31,612 people reported to have side effects when taking Vitamin d3.
Among them, 11 people (0.03%) have Pigmentation disorder.

Could Vitamin d3 cause Pigmentation disorder?

Among these 11 people:

What is the gender of people who have Pigmentation disorder when taking Vitamin d3? *

female: 87.5 %
male: 12.5 %

What is the age of people who have Pigmentation disorder when taking Vitamin d3? *

What are other drugs people take besides Vitamin d3? *

What are other side effects people have besides Pigmentation disorder? *

Rashes (redness): 5 people, 45.45%
Fatigue (feeling of tiredness): 4 people, 36.36%
Headache (pain in head): 4 people, 36.36%
Itching: 3 people, 27.27%
Nausea And Vomiting: 3 people, 27.27%
Nausea (feeling of having an urge to vomit): 3 people, 27.27%
Feeling Abnormal: 3 people, 27.27%
Dizziness: 3 people, 27.27%
Depression: 3 people, 27.27%
Weight Increased: 3 people, 27.27%

What are the existing conditions these people have? *

Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 2 people, 18.18%
Upper Respiratory Tract Infection: 1 person, 9.09%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 9.09%
Angiomyolipoma (most common benign tumour of the kidney): 1 person, 9.09%
Blood Uric Acid Increased: 1 person, 9.09%
Breast Cancer: 1 person, 9.09%
Diabetes: 1 person, 9.09%
Infection: 1 person, 9.09%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 9.09%
Nasal Disorder (diseases of nose): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamin d3 and have Pigmentation disorder?

- Check whether Pigmentation disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vitamin d3:

Vitamin d3 (32,171 reports)

Browse all side effects of Vitamin d3:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pigmentation disorder:

Pigmentation disorder (642 drugs)

Browse all the conditions that are associated with Pigmentation disorder:

Pigmentation disorder (771 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cholecalciferol (the active ingredients of Vitamin d3) and Vitamin d3 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.