Vitamin e and Cholangitis - a phase IV clinical study of FDA data
Summary:
Cholangitis is reported as a side effect among people who take Vitamin e (tocopherols and tocotrienols), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Prednisone, and have Gastroesophageal reflux disease.
The phase IV clinical study analyzes which people have Cholangitis when taking Vitamin e. It is created by eHealthMe based on reports of 41,364 people who have side effects when taking Vitamin e from the FDA, and is updated regularly.
What is Vitamin e?
Vitamin e has active ingredients of tocopherols and tocotrienols. It is often used in vitamin supplementation. eHealthMe is studying from 42,279 Vitamin e users. Check the latest studies of Vitamin e.
What is Cholangitis?
Cholangitis (infection of the bile duct) is found to be associated with 657 drugs and 749 conditions by eHealthMe. Check the latest studies of Cholangitis.
41,364 people reported to have side effects when taking Vitamin e.
Among them, 11 people (0.03%) have Cholangitis.

Among these 11 people:
How long have people been on Vitamin e when they have Cholangitis? *
- < 1 month: 0.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 100 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Cholangitis when taking Vitamin e? *
- female: 63.64 %
- male: 36.36 %
What is the age of people who have Cholangitis when taking Vitamin e? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 25 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 25 %
- 50-59: 25 %
- 60+: 25 %
What are other drugs people take besides Vitamin e? *
- Vitamin D: 2 people, 18.18%
- Tylenol: 2 people, 18.18%
- Rifampin: 2 people, 18.18%
- Vitamins: 2 people, 18.18%
- Bylvay: 2 people, 18.18%
- Januvia: 2 people, 18.18%
- Prednisone: 2 people, 18.18%
- Zocor: 1 person, 9.09%
- Detrol: 1 person, 9.09%
- Crestor: 1 person, 9.09%
What are other side effects people have besides Cholangitis? *
- Abdominal Pain: 4 people, 36.36%
- Abdominal Distension: 3 people, 27.27%
- Melaena (the passage of black, tarry stools): 3 people, 27.27%
- Gallstones (stone formation by bile component): 3 people, 27.27%
- Hepatomegaly (abnormal enlargement of the liver): 3 people, 27.27%
- Diarrhea: 3 people, 27.27%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 27.27%
- Thrombocytopenia (decrease of platelets in blood): 2 people, 18.18%
- Pleural Effusion (water on the lungs): 2 people, 18.18%
- Abdominal Pain Upper: 2 people, 18.18%
What are the existing conditions these people have? *
- Type 2 Diabetes: 2 people, 18.18%
- Pancreatic Carcinoma (pancreatic cancer): 2 people, 18.18%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 18.18%
- Stable Angina (a constant chest pain): 1 person, 9.09%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 9.09%
- Nephrogenic Anaemia (anaemia due to kidney disease): 1 person, 9.09%
- Iron Deficiency: 1 person, 9.09%
- High Blood Pressure: 1 person, 9.09%
- High Blood Cholesterol: 1 person, 9.09%
- Erection Problems: 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Vitamin e and have Cholangitis?
- Check whether Cholangitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Vitamin e:
- Vitamin e (42,279 reports)
Cholangitis treatments and more:
- Cholangitis (7,720 reports)
How severe was Cholangitis and when was it recovered:
Expand to all the drugs that have ingredients of tocopherols and tocotrienols:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Vitamin e:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Cholangitis:
- Cholangitis (657 drugs)
Browse all the conditions that are associated with Cholangitis:
- Cholangitis (749 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on tocopherols and tocotrienols (the active ingredients of Vitamin e) and Vitamin e (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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