Vitamin e and Peripheral arterial occlusive disease - a phase IV clinical study of FDA data

Summary:

Peripheral arterial occlusive disease is reported as a side effect among people who take Vitamin e (tocopherols and tocotrienols), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Metformin, and have High blood pressure.

The phase IV clinical study analyzes which people have Peripheral arterial occlusive disease when taking Vitamin e. It is created by eHealthMe based on reports of 41,364 people who have side effects when taking Vitamin e from the FDA, and is updated regularly.

What is Vitamin e?

Vitamin e has active ingredients of tocopherols and tocotrienols. It is often used in vitamin supplementation. eHealthMe is studying from 42,279 Vitamin e users. Check the latest studies of Vitamin e.

What is Peripheral arterial occlusive disease?

Peripheral arterial occlusive disease (reproducible ischemic muscle pain) is found to be associated with 538 drugs and 682 conditions by eHealthMe. Check the latest studies of Peripheral arterial occlusive disease.

On Jul, 18, 2026

41,364 people reported to have side effects when taking Vitamin e.
Among them, 15 people (0.04%) have Peripheral arterial occlusive disease.

Could Vitamin e cause Peripheral arterial occlusive disease?

Among these 15 people:

How long have people been on Vitamin e when they have Peripheral arterial occlusive disease? *

What is the gender of people who have Peripheral arterial occlusive disease when taking Vitamin e? *

female: 61.54 %
male: 38.46 %

What is the age of people who have Peripheral arterial occlusive disease when taking Vitamin e? *

What are other drugs people take besides Vitamin e? *

What are other side effects people have besides Peripheral arterial occlusive disease? *

Weight Decreased: 4 people, 26.67%
High Blood Pressure: 4 people, 26.67%
Stress And Anxiety: 4 people, 26.67%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 20.00%
Back Pain: 3 people, 20.00%
Neuropathy Peripheral (surface nerve damage): 3 people, 20.00%
Pneumonia: 3 people, 20.00%
Diverticulum Intestinal (a pouch that is attached to the first part of the small intestine): 3 people, 20.00%
Renal Cyst (kidney cyst): 3 people, 20.00%
Pain In Extremity: 3 people, 20.00%

What are the existing conditions these people have? *

High Blood Pressure: 3 people, 20.00%
Type 2 Diabetes: 2 people, 13.33%
Bone Disorder: 2 people, 13.33%
Breast Cancer Female: 2 people, 13.33%
Cardiac Disorder: 2 people, 13.33%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 2 people, 13.33%
Diabetes: 2 people, 13.33%
Dyslipidaemia (abnormal amount of lipids): 2 people, 13.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 13.33%
Neuropathy Peripheral (surface nerve damage): 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamin e and have Peripheral arterial occlusive disease?

- Check whether Peripheral arterial occlusive disease is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vitamin e:

Vitamin e (42,279 reports)

Browse all side effects of Vitamin e:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Peripheral arterial occlusive disease:

Peripheral arterial occlusive disease (538 drugs)

Browse all the conditions that are associated with Peripheral arterial occlusive disease:

Peripheral arterial occlusive disease (682 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tocopherols and tocotrienols (the active ingredients of Vitamin e) and Vitamin e (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.