Vitamins and Intervertebral disc space narrowing - a phase IV clinical study of FDA data

Summary:

Intervertebral disc space narrowing is reported as a side effect among people who take Vitamins (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e), especially for people who are female, 60+ old, have been taking the drug for 10+ years also take Zometa, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Intervertebral disc space narrowing when taking Vitamins. It is created by eHealthMe based on reports of 121,858 people who have side effects when taking Vitamins from the FDA, and is updated regularly.

What is Vitamins?

Vitamins has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 122,457 Vitamins users. Check the latest studies of Vitamins.

What is Intervertebral disc space narrowing?

Intervertebral disc space narrowing (spinal disc space narrowing) is found to be associated with 452 drugs and 316 conditions by eHealthMe. Check the latest studies of Intervertebral disc space narrowing.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

121,858 people reported to have side effects when taking Vitamins.
Among them, 69 people (0.06%) have Intervertebral disc space narrowing.

Could Vitamins cause Intervertebral disc space narrowing?

Among these 69 people:

How long have people been on Vitamins when they have Intervertebral disc space narrowing? *

What is the gender of people who have Intervertebral disc space narrowing when taking Vitamins? *

female: 69.7 %
male: 30.3 %

What is the age of people who have Intervertebral disc space narrowing when taking Vitamins? *

What are other drugs people take besides Vitamins? *

What are other side effects people have besides Intervertebral disc space narrowing? *

Osteonecrosis Of Jaw (death of bone of jaw): 43 people, 62.32%
Stress And Anxiety: 42 people, 60.87%
Intervertebral Disc Protrusion (spinal disc protrusion): 41 people, 59.42%
Pain In Extremity: 40 people, 57.97%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 40 people, 57.97%
Depression: 39 people, 56.52%
Back Pain: 39 people, 56.52%
Joint Pain: 36 people, 52.17%
Pain: 36 people, 52.17%
Spinal Osteoarthritis (joint cartilage loss in spine): 34 people, 49.28%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 23 people, 33.33%
Breast Cancer: 12 people, 17.39%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 12 people, 17.39%
Osteoporosis (bones weak and more likely to break): 11 people, 15.94%
Metastases To Bone (cancer spreads to bone): 10 people, 14.49%
Depression: 8 people, 11.59%
Bone Disorder: 5 people, 7.25%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 7.25%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 4 people, 5.80%
Anaemia (lack of blood): 4 people, 5.80%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamins and have Intervertebral disc space narrowing?

- Check whether Intervertebral disc space narrowing is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vitamins:

Vitamins (122,457 reports)

Intervertebral disc space narrowing treatments and more:

Intervertebral disc space narrowing (1,486 reports)

How severe was Intervertebral disc space narrowing and when was it recovered:

Intervertebral disc space narrowing in Vitamins

Expand to all the drugs that have ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e:

Intervertebral disc space narrowing and drugs with ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vitamins:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intervertebral disc space narrowing:

Intervertebral disc space narrowing (452 drugs)

Browse all the conditions that are associated with Intervertebral disc space narrowing:

Intervertebral disc space narrowing (316 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (the active ingredients of Vitamins) and Vitamins (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.