Vytorin and Appendicitis - a phase IV clinical study of FDA data

Summary:

Appendicitis is reported as a side effect among people who take Vytorin (ezetimibe; simvastatin), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Fosamax, and have Hyperlipidaemia.

The phase IV clinical study analyzes which people have Appendicitis when taking Vytorin. It is created by eHealthMe based on reports of 19,379 people who have side effects when taking Vytorin from the FDA, and is updated regularly.

What is Vytorin?

Vytorin has active ingredients of ezetimibe; simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 20,084 Vytorin users. Check the latest studies of Vytorin.

What is Appendicitis?

Appendicitis (inflammation of the appendix) is found to be associated with 835 drugs and 895 conditions by eHealthMe. Check the latest studies of Appendicitis.

On Jul, 16, 2026

19,379 people reported to have side effects when taking Vytorin.
Among them, 23 people (0.12%) have Appendicitis.

Among these 23 people:

How long have people been on Vytorin when they have Appendicitis? *

What is the gender of people who have Appendicitis when taking Vytorin? *

female: 58.82 %
male: 41.18 %

What is the age of people who have Appendicitis when taking Vytorin? *

What are other drugs people take besides Vytorin? *

Fosamax: 5 people, 21.74%
Paxil: 4 people, 17.39%
Crestor: 4 people, 17.39%
Lipitor: 4 people, 17.39%
Januvia: 4 people, 17.39%
Dicyclomine Hydrochloride: 4 people, 17.39%
Lescol Xl: 4 people, 17.39%
Zetia: 4 people, 17.39%
Benicar Hct: 3 people, 13.04%
Evista: 3 people, 13.04%

What are other side effects people have besides Appendicitis? *

Kidney Stones: 5 people, 21.74%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 4 people, 17.39%
Pain: 4 people, 17.39%
Bone Disorder: 4 people, 17.39%
Femur Fracture: 4 people, 17.39%
Broken Bone: 4 people, 17.39%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 4 people, 17.39%
Bundle Branch Block Right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle): 4 people, 17.39%
Low Turnover Osteopathy (slow removal of old bone and its replacement by new bone): 4 people, 17.39%
Limb Injury: 4 people, 17.39%

What are the existing conditions these people have? *

Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 21.74%
Osteoporosis (bones weak and more likely to break): 4 people, 17.39%
Diabetes: 4 people, 17.39%
Irritable Bowel Syndrome: 4 people, 17.39%
Joint Pain: 3 people, 13.04%
Stress And Anxiety: 3 people, 13.04%
Pain: 3 people, 13.04%
Muscle Aches (muscle pain): 3 people, 13.04%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 13.04%
Type 2 Diabetes: 3 people, 13.04%

* Approximation only. Some reports may have incomplete information.

Do you take Vytorin and have Appendicitis?

- Check whether Appendicitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vytorin:

Vytorin (20,084 reports)

Appendicitis treatments and more:

Appendicitis (11,953 reports)

Browse all side effects of Vytorin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Appendicitis:

Appendicitis (835 drugs)

Browse all the conditions that are associated with Appendicitis:

Appendicitis (895 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ezetimibe; simvastatin (the active ingredients of Vytorin) and Vytorin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.