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Vyvanse and Infectious mononucleosis - a phase IV clinical study of FDA data

Summary:

Infectious mononucleosis is reported as a side effect among people who take Vyvanse (lisdexamfetamine dimesylate), especially for people who are female, 10-19 old, have been taking the drug for 6 - 12 months also take Melatonin, and have Hair loss.

The phase IV clinical study analyzes which people have Infectious mononucleosis when taking Vyvanse. It is created by eHealthMe based on reports of 28,083 people who have side effects when taking Vyvanse from the FDA, and is updated regularly.

What is Vyvanse?

Vyvanse has active ingredients of lisdexamfetamine dimesylate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 35,872 Vyvanse users. Check the latest studies of Vyvanse.

What is Infectious mononucleosis?

Infectious mononucleosis (infection usually caused by the epstein-barr virus) is found to be associated with 347 drugs and 443 conditions by eHealthMe. Check the latest studies of Infectious mononucleosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

28,083 people reported to have side effects when taking Vyvanse.
Among them, 13 people (0.05%) have Infectious mononucleosis.

Could Vyvanse cause Infectious mononucleosis?

Among these 13 people:

How long have people been on Vyvanse when they have Infectious mononucleosis? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 50 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Infectious mononucleosis when taking Vyvanse? *

  • female: 60 %
  • male: 40 %

What is the age of people who have Infectious mononucleosis when taking Vyvanse? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 60 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 40 %
  • 60+: 0.0 %

What are other drugs people take besides Vyvanse? *

  1. Premarin: 3 people, 23.08%
  2. Xeljanz: 3 people, 23.08%
  3. Melatonin: 3 people, 23.08%
  4. Prozac: 2 people, 15.38%
  5. Calcium Carbonate: 2 people, 15.38%
  6. Inflectra: 2 people, 15.38%
  7. Mesalamine: 2 people, 15.38%
  8. Pentasa: 2 people, 15.38%
  9. Advil: 2 people, 15.38%
  10. Tylenol: 2 people, 15.38%

What are other side effects people have besides Infectious mononucleosis? *

  1. Fatigue (feeling of tiredness): 4 people, 30.77%
  2. Oropharyngeal Pain: 4 people, 30.77%
  3. Fever: 3 people, 23.08%
  4. Malaise (a feeling of general discomfort or uneasiness): 3 people, 23.08%
  5. Weight Decreased: 3 people, 23.08%
  6. Urticaria (rash of round, red welts on the skin that itch intensely): 3 people, 23.08%
  7. Urination - Painful: 2 people, 15.38%
  8. Urinary Tract Pain: 2 people, 15.38%
  9. Joint Pain: 2 people, 15.38%
  10. Ligament Sprain (ligament stretched): 2 people, 15.38%

What are the existing conditions these people have? *

  1. Hair Loss: 3 people, 23.08%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 15.38%
  3. Alopecia Areata (patchy baldness that typically begins with rapid hair loss): 2 people, 15.38%
  4. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 7.69%
  5. Drowsiness: 1 person, 7.69%
  6. Complement Factor Abnormal: 1 person, 7.69%
  7. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 7.69%
  8. Asthma: 1 person, 7.69%
  9. Alcoholism (problems with alcohol): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Vyvanse and have Infectious mononucleosis?

- Check whether Infectious mononucleosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vyvanse:

Infectious mononucleosis treatments and more:

How severe was Infectious mononucleosis and when was it recovered:

Expand to all the drugs that have ingredients of lisdexamfetamine dimesylate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vyvanse:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Infectious mononucleosis:

Browse all the conditions that are associated with Infectious mononucleosis:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on lisdexamfetamine dimesylate (the active ingredients of Vyvanse) and Vyvanse (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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