Warfarin sodium and Sinus node dysfunction - a phase IV clinical study of FDA data

Summary:

Sinus node dysfunction is reported as a side effect among people who take Warfarin sodium (warfarin sodium), especially for people who are male, 60+ old, also take Digoxin, and have High blood pressure.

The phase IV clinical study analyzes which people have Sinus node dysfunction when taking Warfarin sodium. It is created by eHealthMe based on reports of 67,331 people who have side effects when taking Warfarin sodium from the FDA, and is updated regularly.

What is Warfarin sodium?

Warfarin sodium has active ingredients of warfarin sodium. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 71,167 Warfarin sodium users. Check the latest studies of Warfarin sodium.

What is Sinus node dysfunction?

Sinus node dysfunction (a group of abnormal heart rhythms) is found to be associated with 1,226 drugs and 836 conditions by eHealthMe. Check the latest studies of Sinus node dysfunction.

On Dec, 08, 2025

67,331 people reported to have side effects when taking Warfarin sodium.
Among them, 104 people (0.15%) have Sinus node dysfunction.

Could Warfarin sodium cause Sinus node dysfunction?

Among these 104 people:

What is the gender of people who have Sinus node dysfunction when taking Warfarin sodium? *

female: 35.92 %
male: 64.08 %

What is the age of people who have Sinus node dysfunction when taking Warfarin sodium? *

What are other drugs people take besides Warfarin sodium? *

What are other side effects people have besides Sinus node dysfunction? *

Bradycardia (abnormally slow heart action): 30 people, 28.85%
Oedema Peripheral (superficial swelling): 30 people, 28.85%
Cardiac Failure Congestive: 30 people, 28.85%
Dizziness: 30 people, 28.85%
High Blood Pressure: 29 people, 27.88%
Dyspnea (difficult or laboured breathing): 27 people, 25.96%
Weakness: 24 people, 23.08%
Stress And Anxiety: 22 people, 21.15%
Pain: 21 people, 20.19%
Nausea (feeling of having an urge to vomit): 18 people, 17.31%

What are the existing conditions these people have? *

High Blood Pressure: 18 people, 17.31%
Dyspnea (difficult or laboured breathing): 10 people, 9.62%
Depression: 9 people, 8.65%
Osteomyelitis (infection of bone): 9 people, 8.65%
Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 5 people, 4.81%
Osteoporosis (bones weak and more likely to break): 5 people, 4.81%
Cardiac Failure Congestive: 5 people, 4.81%
Neuroendocrine Tumor: 5 people, 4.81%
Cardiac Disorder: 5 people, 4.81%
Renal Cell Carcinoma (a kidney cancer): 5 people, 4.81%

* Approximation only. Some reports may have incomplete information.

Do you take Warfarin sodium and have Sinus node dysfunction?

- Check whether Sinus node dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Warfarin sodium:

Warfarin sodium (71,167 reports)

Common Warfarin sodium side effects:

Browse all side effects of Warfarin sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Sinus node dysfunction:

Browse all the drugs that are associated with Sinus node dysfunction:

Sinus node dysfunction (1,226 drugs)

Common conditions associated with Sinus node dysfunction:

Hypertension: 487 reports
Blood pressure increased: 483 reports
Atrial fibrillation: 337 reports
Diabetes mellitus aggravated: 222 reports
Diabetes: 221 reports
Multiple myeloma: 169 reports
Osteoporosis: 163 reports
Thin bones: 153 reports
Rheumatoid arthritis: 124 reports

Browse all the conditions that are associated with Sinus node dysfunction:

Sinus node dysfunction (836 conditions)

Drugs similar to Warfarin sodium and Sinus node dysfunction :

How the study uses the data?

The study uses data from the FDA. It is based on warfarin sodium (the active ingredients of Warfarin sodium) and Warfarin sodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.