Wegovy and Menstrual disorder - a phase IV clinical study of FDA data

Summary:

Menstrual disorder is reported as a side effect among people who take Wegovy (semaglutide), especially for people who are 50-59 old, have been taking the drug for 1 - 6 months also take Fluoxetine, and have Weight decreased.

The phase IV clinical study analyzes which people have Menstrual disorder when taking Wegovy. It is created by eHealthMe based on reports of 4,836 people who have side effects when taking Wegovy from the FDA, and is updated regularly.

What is Wegovy?

Wegovy has active ingredients of semaglutide. It is often used in weight loss. eHealthMe is studying from 4,885 Wegovy users. Check the latest studies of Wegovy.

What is Menstrual disorder?

Menstrual disorder (disease of menstrual cycle) is found to be associated with 530 drugs and 580 conditions by eHealthMe. Check the latest studies of Menstrual disorder.



On Jul, 06, 2026

4,836 people reported to have side effects when taking Wegovy.
Among them, 12 people (0.25%) have Menstrual disorder.

Could Wegovy cause Menstrual disorder?

Among these 12 people:

How long have people been on Wegovy when they have Menstrual disorder? *

  • < 1 month: 33.33 %
  • 1 - 6 months: 66.67 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the age of people who have Menstrual disorder when taking Wegovy? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 28.57 %
  • 30-39: 14.29 %
  • 40-49: 28.57 %
  • 50-59: 28.57 %
  • 60+: 0.0 %

What are other drugs people take besides Wegovy? *

  1. Nexium: 1 person, 8.33%
  2. Metformin Hydrochloride: 1 person, 8.33%
  3. Fluoxetine: 1 person, 8.33%

What are other side effects people have besides Menstrual disorder? *

  1. Nausea (feeling of having an urge to vomit): 4 people, 33.33%
  2. Dysmenorrhea (painful menstruation): 2 people, 16.67%
  3. Weakness: 1 person, 8.33%
  4. Vaginal Bleeding Between Periods: 1 person, 8.33%
  5. Vaginal Bleeding: 1 person, 8.33%
  6. Oropharyngeal Blistering (blister of oropharynx): 1 person, 8.33%
  7. Oral Mucosal Blistering (mouth ulcer): 1 person, 8.33%
  8. Nausea And Vomiting: 1 person, 8.33%
  9. Indigestion: 1 person, 8.33%
  10. Headache (pain in head): 1 person, 8.33%

What are the existing conditions these people have? *

  1. Weight Decreased: 2 people, 16.67%
  2. Stress And Anxiety: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Wegovy and have Menstrual disorder?

- Check whether Menstrual disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Wegovy:

Menstrual disorder treatments and more:

How severe was Menstrual disorder and when was it recovered:

Expand to all the drugs that have ingredients of semaglutide:

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Wegovy:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Menstrual disorder:

Browse all the conditions that are associated with Menstrual disorder:


How the study uses the data?

The study uses data from the FDA. It is based on semaglutide (the active ingredients of Wegovy) and Wegovy (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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