Wellbutrin sr and Abnormal behavior - a phase IV clinical study of FDA data

Summary:

Abnormal behavior is reported as a side effect among people who take Wellbutrin sr (bupropion hydrochloride), especially for people who are male, 40-49 old, have been taking the drug for < 1 month also take Ambien, and have Pain.

The phase IV clinical study analyzes which people have Abnormal behavior when taking Wellbutrin sr. It is created by eHealthMe based on reports of 9,388 people who have side effects when taking Wellbutrin sr from the FDA, and is updated regularly.

What is Wellbutrin sr?

Wellbutrin sr has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 13,112 Wellbutrin sr users. Check the latest studies of Wellbutrin sr.

What is Abnormal behavior?

Abnormal behavior is found to be associated with 1,360 drugs and 1,957 conditions by eHealthMe. Check the latest studies of Abnormal behavior.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

9,388 people reported to have side effects when taking Wellbutrin sr.
Among them, 53 people (0.56%) have Abnormal behavior.

Could Wellbutrin sr cause Abnormal behavior?

Among these 53 people:

How long have people been on Wellbutrin sr when they have Abnormal behavior? *

What is the gender of people who have Abnormal behavior when taking Wellbutrin sr? *

female: 48.08 %
male: 51.92 %

What is the age of people who have Abnormal behavior when taking Wellbutrin sr? *

What are other drugs people take besides Wellbutrin sr? *

What are other side effects people have besides Abnormal behavior? *

Insomnia (sleeplessness): 14 people, 26.42%
Aggression: 13 people, 24.53%
Completed Suicide (act of taking one's own life): 12 people, 22.64%
Memory Loss: 11 people, 20.75%
Drug Ineffective: 10 people, 18.87%
Fatigue (feeling of tiredness): 10 people, 18.87%
Suicidal Ideation: 9 people, 16.98%
Crying: 8 people, 15.09%
Disturbance In Attention: 8 people, 15.09%
Confusional State: 7 people, 13.21%

What are the existing conditions these people have? *

Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 5 people, 9.43%
Pain: 5 people, 9.43%
Insomnia (sleeplessness): 3 people, 5.66%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 2 people, 3.77%
Hallucinations (sensations that appear real but are created by your mind): 1 person, 1.89%
Back Pain: 1 person, 1.89%
Bipolar Disorder (mood disorder): 1 person, 1.89%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 1 person, 1.89%
Calculus Bladder (bladder stone): 1 person, 1.89%
Delusion (a false belief or opinion): 1 person, 1.89%

* Approximation only. Some reports may have incomplete information.

Do you take Wellbutrin sr and have Abnormal behavior?

- Check whether Abnormal behavior is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Wellbutrin sr:

Wellbutrin sr (13,112 reports)

Browse all side effects of Wellbutrin sr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Abnormal behavior:

Abnormal behavior (1,360 drugs)

Browse all the conditions that are associated with Abnormal behavior:

Abnormal behavior (1,957 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on bupropion hydrochloride (the active ingredients of Wellbutrin sr) and Wellbutrin sr (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.