Wellbutrin sr and Hypothyroidism - a phase IV clinical study of FDA data

Summary:

Hypothyroidism is reported as a side effect among people who take Wellbutrin sr (bupropion hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Lexapro, and have Pain.

The phase IV clinical study analyzes which people have Hypothyroidism when taking Wellbutrin sr. It is created by eHealthMe based on reports of 9,388 people who have side effects when taking Wellbutrin sr from the FDA, and is updated regularly.

What is Wellbutrin sr?

Wellbutrin sr has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 13,112 Wellbutrin sr users. Check the latest studies of Wellbutrin sr.

What is Hypothyroidism?

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development) is found to be associated with 1,616 drugs and 2,600 conditions by eHealthMe. Check the latest studies of Hypothyroidism.

On May, 30, 2026

9,388 people reported to have side effects when taking Wellbutrin sr.
Among them, 40 people (0.43%) have Hypothyroidism.

Could Wellbutrin sr cause Hypothyroidism?

Among these 40 people:

How long have people been on Wellbutrin sr when they have Hypothyroidism? *

What is the gender of people who have Hypothyroidism when taking Wellbutrin sr? *

female: 77.5 %
male: 22.5 %

What is the age of people who have Hypothyroidism when taking Wellbutrin sr? *

What are other drugs people take besides Wellbutrin sr? *

What are other side effects people have besides Hypothyroidism? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 15 people, 37.50%
Asthma: 11 people, 27.50%
Dyspnea (difficult or laboured breathing): 9 people, 22.50%
Deformity (disfigurement): 8 people, 20.00%
Osteoporosis (bones weak and more likely to break): 7 people, 17.50%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 7 people, 17.50%
Drug Exposure During Pregnancy: 7 people, 17.50%
Pain: 7 people, 17.50%
Injury: 6 people, 15.00%
Pain In Extremity: 6 people, 15.00%

What are the existing conditions these people have? *

Pain: 7 people, 17.50%
High Blood Pressure: 6 people, 15.00%
Birth Control: 5 people, 12.50%
High Blood Cholesterol: 5 people, 12.50%
Infection: 5 people, 12.50%
Urinary Tract Infection: 5 people, 12.50%
Osteoporosis (bones weak and more likely to break): 5 people, 12.50%
Vasculitis (inflammation of a blood vessel or blood vessels): 4 people, 10.00%
Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 4 people, 10.00%
Ankylosing Spondylitis (type of arthritis affecting the spine): 4 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Wellbutrin sr and have Hypothyroidism?

- Check whether Hypothyroidism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Wellbutrin sr:

Wellbutrin sr (13,112 reports)

Hypothyroidism treatments and more:

Hypothyroidism (168,067 reports)

Browse all side effects of Wellbutrin sr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypothyroidism:

Hypothyroidism (1,616 drugs)

Browse all the conditions that are associated with Hypothyroidism:

Hypothyroidism (2,600 conditions)

Related publications that referenced our studies

Ezeji GC, Inoue T, Bahtiyar G, Sacerdote A, "Hallucinations associated with miglitol use in a patient with chronic kidney disease and hypothyroidism", BMJ case reports, 2015 Feb .
Ezeji GC, Inoue T, Bahtiyar G, Sacerdote A, "Hallucinations associated with miglitol use in a patient with chronic kidney disease and hypothyroidism", BMJ case reports, 2015 Feb .

How the study uses the data?

The study uses data from the FDA. It is based on bupropion hydrochloride (the active ingredients of Wellbutrin sr) and Wellbutrin sr (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.