Wellbutrin sr and Interstitial lung disease - a phase IV clinical study of FDA data

Summary:

Interstitial lung disease is reported as a side effect among people who take Wellbutrin sr (bupropion hydrochloride), especially for people who are male, 40-49 old, have been taking the drug for 1 - 6 months also take Neurontin, and have Ankylosing spondylitis.

The phase IV clinical study analyzes which people have Interstitial lung disease when taking Wellbutrin sr. It is created by eHealthMe based on reports of 9,388 people who have side effects when taking Wellbutrin sr from the FDA, and is updated regularly.

What is Wellbutrin sr?

Wellbutrin sr has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 13,112 Wellbutrin sr users. Check the latest studies of Wellbutrin sr.

What is Interstitial lung disease?

Interstitial lung disease is found to be associated with 1,499 drugs and 1,840 conditions by eHealthMe. Check the latest studies of Interstitial lung disease.

On Aug, 11, 2026

9,388 people reported to have side effects when taking Wellbutrin sr.
Among them, 15 people (0.16%) have Interstitial lung disease.

Could Wellbutrin sr cause Interstitial lung disease?

Among these 15 people:

How long have people been on Wellbutrin sr when they have Interstitial lung disease? *

What is the gender of people who have Interstitial lung disease when taking Wellbutrin sr? *

female: 30.77 %
male: 69.23 %

What is the age of people who have Interstitial lung disease when taking Wellbutrin sr? *

What are other drugs people take besides Wellbutrin sr? *

What are other side effects people have besides Interstitial lung disease? *

Osteopenia (a condition where bone mineral density is lower than normal): 8 people, 53.33%
Pain In Extremity: 8 people, 53.33%
Injury: 8 people, 53.33%
Pain: 8 people, 53.33%
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 8 people, 53.33%
Compression Fracture (fracture due to pressure caused by injury): 8 people, 53.33%
Osteoporosis (bones weak and more likely to break): 8 people, 53.33%
Fatigue (feeling of tiredness): 7 people, 46.67%
Constipation: 7 people, 46.67%
Pneumonia: 7 people, 46.67%

What are the existing conditions these people have? *

Sleep Disorder: 2 people, 13.33%
Pain: 2 people, 13.33%
Neoplasm Malignant (cancer tumour): 2 people, 13.33%
Nausea (feeling of having an urge to vomit): 2 people, 13.33%
Multiple Myeloma (cancer of the plasma cells): 2 people, 13.33%
Lung Cancer - Non-Small Cell (lung cancer): 2 people, 13.33%
Cough: 2 people, 13.33%
Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 13.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.67%
Renal Disorder (kidney disease): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Wellbutrin sr and have Interstitial lung disease?

- Check whether Interstitial lung disease is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Wellbutrin sr:

Wellbutrin sr (13,112 reports)

Browse all side effects of Wellbutrin sr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Interstitial lung disease:

Interstitial lung disease (1,499 drugs)

Browse all the conditions that are associated with Interstitial lung disease:

Interstitial lung disease (1,840 conditions)

Related publications that referenced our studies

Thangakunam B, Christopher DJ, Mathews V, Srivastava A, "Mesenchymal stromal stem cell therapy in advanced interstitial lung disease-Anaphylaxis and short-term follow-up", Lung India: official organ of Indian Chest Society, 2015 Jan .
Kato, M., Oiso, N., Nozaki, Y., Inoue, A., Hosono, Y., Funauchi, M., ... & Kawada, A., "Antitumor necrosis factor alpha inhibitor‐induced dermatomyositis and interstitial lung disease with anti‐PL 12 autoantibody: Signs of antisynthetase syndrome", The Journal of dermatology, 2012 Jan .
Thangakunam B, Christopher DJ, Mathews V, Srivastava A, "Mesenchymal stromal stem cell therapy in advanced interstitial lung disease-Anaphylaxis and short-term follow-up", Lung India: official organ of Indian Chest Society, 2015 Jan .
Kato, M., Oiso, N., Nozaki, Y., Inoue, A., Hosono, Y., Funauchi, M., ... & Kawada, A., "Antitumor necrosis factor alpha inhibitor‐induced dermatomyositis and interstitial lung disease with anti‐PL 12 autoantibody: Signs of antisynthetase syndrome", The Journal of dermatology, 2012 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on bupropion hydrochloride (the active ingredients of Wellbutrin sr) and Wellbutrin sr (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.