Wellbutrin sr and Sleep apnea syndrome - a phase IV clinical study of FDA data

Summary:

Sleep apnea syndrome is reported as a side effect among people who take Wellbutrin sr (bupropion hydrochloride), especially for people who are female, 30-39 old, have been taking the drug for < 1 month also take Paxil, and have Narcolepsy.

The phase IV clinical study analyzes which people have Sleep apnea syndrome when taking Wellbutrin sr. It is created by eHealthMe based on reports of 9,388 people who have side effects when taking Wellbutrin sr from the FDA, and is updated regularly.

What is Wellbutrin sr?

Wellbutrin sr has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 13,112 Wellbutrin sr users. Check the latest studies of Wellbutrin sr.

What is Sleep apnea syndrome?

Sleep apnea syndrome is found to be associated with 1,537 drugs and 1,371 conditions by eHealthMe. Check the latest studies of Sleep apnea syndrome.



On Jul, 06, 2026

9,388 people reported to have side effects when taking Wellbutrin sr.
Among them, 83 people (0.88%) have Sleep apnea syndrome.

Could Wellbutrin sr cause Sleep apnea syndrome?

Among these 83 people:

How long have people been on Wellbutrin sr when they have Sleep apnea syndrome? *

  • < 1 month: 40 %
  • 1 - 6 months: 20 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 40 %

What is the gender of people who have Sleep apnea syndrome when taking Wellbutrin sr? *

  • female: 72.29 %
  • male: 27.71 %

What is the age of people who have Sleep apnea syndrome when taking Wellbutrin sr? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 39.73 %
  • 40-49: 26.03 %
  • 50-59: 24.66 %
  • 60+: 9.59 %

What are other drugs people take besides Wellbutrin sr? *

  1. Celexa: 38 people, 45.78%
  2. Paxil: 38 people, 45.78%
  3. Skelaxin: 34 people, 40.96%
  4. Flonase: 34 people, 40.96%
  5. Ativan: 32 people, 38.55%
  6. Zometa: 31 people, 37.35%
  7. Aranesp: 27 people, 32.53%
  8. Zyprexa: 27 people, 32.53%
  9. Neupogen: 25 people, 30.12%
  10. Gabapentin: 25 people, 30.12%

What are other side effects people have besides Sleep apnea syndrome? *

  1. High Blood Cholesterol: 40 people, 48.19%
  2. Back Pain: 40 people, 48.19%
  3. Pain: 37 people, 44.58%
  4. Dyspnea (difficult or laboured breathing): 36 people, 43.37%
  5. Weight Increased: 35 people, 42.17%
  6. Fatigue (feeling of tiredness): 34 people, 40.96%
  7. Emotional Distress: 33 people, 39.76%
  8. Memory Loss: 33 people, 39.76%
  9. Drowsiness: 33 people, 39.76%
  10. Fever: 32 people, 38.55%

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 18 people, 21.69%
  2. Bone Density Decreased: 13 people, 15.66%
  3. Pain: 13 people, 15.66%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 13.25%
  5. High Blood Pressure: 9 people, 10.84%
  6. Fatigue (feeling of tiredness): 8 people, 9.64%
  7. Multiple Myeloma (cancer of the plasma cells): 8 people, 9.64%
  8. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 8.43%
  9. High Blood Cholesterol: 6 people, 7.23%
  10. Metastases To Bone (cancer spreads to bone): 6 people, 7.23%

* Approximation only. Some reports may have incomplete information.

Do you take Wellbutrin sr and have Sleep apnea syndrome?

- Check whether Sleep apnea syndrome is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Wellbutrin sr:

Sleep apnea syndrome treatments and more:

How severe was Sleep apnea syndrome and when was it recovered:

Expand to all the drugs that have ingredients of bupropion hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Wellbutrin sr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sleep apnea syndrome:

Browse all the conditions that are associated with Sleep apnea syndrome:


How the study uses the data?

The study uses data from the FDA. It is based on bupropion hydrochloride (the active ingredients of Wellbutrin sr) and Wellbutrin sr (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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