Wellbutrin and Hyperthyroid - a phase IV clinical study of FDA data

Summary:

Hyperthyroid is reported as a side effect among people who take Wellbutrin (bupropion hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Synthroid, and have High blood pressure.

The phase IV clinical study analyzes which people have Hyperthyroid when taking Wellbutrin. It is created by eHealthMe based on reports of 101,581 people who have side effects when taking Wellbutrin from the FDA, and is updated regularly.

What is Wellbutrin?

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 117,078 Wellbutrin users. Check the latest studies of Wellbutrin.

What is Hyperthyroid?

Hyperthyroid is found to be associated with 1,144 drugs and 1,401 conditions by eHealthMe. Check the latest studies of Hyperthyroid.



On Sep, 17, 2025

101,581 people reported to have side effects when taking Wellbutrin.
Among them, 84 people (0.08%) have Hyperthyroid.

Could Wellbutrin cause Hyperthyroid?

Among these 84 people:

How long have people been on Wellbutrin when they have Hyperthyroid? *

  • < 1 month: 12.5 %
  • 1 - 6 months: 62.5 %
  • 6 - 12 months: 12.5 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 12.5 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hyperthyroid when taking Wellbutrin? *

  • female: 91.25 %
  • male: 8.75 %

What is the age of people who have Hyperthyroid when taking Wellbutrin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 4.48 %
  • 20-29: 0.0 %
  • 30-39: 16.42 %
  • 40-49: 29.85 %
  • 50-59: 16.42 %
  • 60+: 32.84 %

What are other drugs people take besides Wellbutrin? *

  1. Synthroid: 24 people, 28.57%
  2. Effexor: 18 people, 21.43%
  3. Ibuprofen: 14 people, 16.67%
  4. Neurontin: 13 people, 15.48%
  5. Lasix: 13 people, 15.48%
  6. Xanax: 13 people, 15.48%
  7. Ativan: 13 people, 15.48%
  8. Levaquin: 12 people, 14.29%
  9. Prilosec: 12 people, 14.29%
  10. Nexium: 12 people, 14.29%

What are other side effects people have besides Hyperthyroid? *

  1. Nausea (feeling of having an urge to vomit): 26 people, 30.95%
  2. Tremor (trembling or shaking movements in one or more parts of your body): 24 people, 28.57%
  3. Dyspnea (difficult or laboured breathing): 23 people, 27.38%
  4. Fatigue (feeling of tiredness): 22 people, 26.19%
  5. Pain: 19 people, 22.62%
  6. High Blood Pressure: 19 people, 22.62%
  7. Weight Decreased: 18 people, 21.43%
  8. Nausea And Vomiting: 18 people, 21.43%
  9. Cough: 17 people, 20.24%
  10. Pneumonia: 14 people, 16.67%

What are the existing conditions these people have? *

  1. High Blood Pressure: 16 people, 19.05%
  2. Pain: 15 people, 17.86%
  3. Asthma: 9 people, 10.71%
  4. Sleep Disorder: 7 people, 8.33%
  5. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 7 people, 8.33%
  6. Insomnia (sleeplessness): 7 people, 8.33%
  7. Breast Cancer: 6 people, 7.14%
  8. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 7.14%
  9. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 5 people, 5.95%
  10. Multiple Myeloma (cancer of the plasma cells): 5 people, 5.95%

* Approximation only. Some reports may have incomplete information.

Do you take Wellbutrin and have Hyperthyroid?

- Check whether Hyperthyroid is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Wellbutrin:

Hyperthyroid treatments and more:

How severe was Hyperthyroid and when was it recovered:

Expand to all the drugs that have ingredients of bupropion hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Wellbutrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperthyroid:

Browse all the conditions that are associated with Hyperthyroid:

Drugs similar to Wellbutrin and Hyperthyroid :


How the study uses the data?

The study uses data from the FDA. It is based on bupropion hydrochloride (the active ingredients of Wellbutrin) and Wellbutrin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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