Xadago and Weakness - a phase IV clinical study of FDA data

Summary:

Weakness is reported as a side effect among people who take Xadago (safinamide mesylate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Rytary, and have Parkinson's disease.

The phase IV clinical study analyzes which people have Weakness when taking Xadago. It is created by eHealthMe based on reports of 1,020 people who have side effects when taking Xadago from the FDA, and is updated regularly.

What is Xadago?

Xadago has active ingredients of safinamide mesylate. eHealthMe is studying from 1,022 Xadago users. Check the latest studies of Xadago.

What is Weakness?

Weakness is found to be associated with 3,641 drugs and 6,611 conditions by eHealthMe. Check the latest studies of Weakness.

On Jul, 10, 2026

1,020 people reported to have side effects when taking Xadago.
Among them, 46 people (4.51%) have Weakness.

Among these 46 people:

How long have people been on Xadago when they have Weakness? *

What is the gender of people who have Weakness when taking Xadago? *

female: 57.78 %
male: 42.22 %

What is the age of people who have Weakness when taking Xadago? *

What are other drugs people take besides Xadago? *

What are other side effects people have besides Weakness? *

Fall: 16 people, 34.78%
Dyskinesia (abnormality or impairment of voluntary movement): 14 people, 30.43%
Fatigue (feeling of tiredness): 11 people, 23.91%
Freezing Phenomenon: 11 people, 23.91%
High Blood Pressure: 10 people, 21.74%
Drowsiness: 9 people, 19.57%
Gait Disturbance: 8 people, 17.39%
Hypotension (abnormally low blood pressure): 8 people, 17.39%
Nausea (feeling of having an urge to vomit): 8 people, 17.39%
Weight Decreased: 8 people, 17.39%

What are the existing conditions these people have? *

Parkinson's Disease: 37 people, 80.43%
On And Off Phenomenon: 5 people, 10.87%
Hallucinations (sensations that appear real but are created by your mind): 4 people, 8.70%
Dyskinesia (abnormality or impairment of voluntary movement): 4 people, 8.70%
Type 2 Diabetes: 3 people, 6.52%
Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 3 people, 6.52%
Fainting (loss of consciousness and postural tone): 2 people, 4.35%
Dizziness: 2 people, 4.35%
Delusion (a false belief or opinion): 2 people, 4.35%
Stress And Anxiety: 1 person, 2.17%

* Approximation only. Some reports may have incomplete information.

Do you take Xadago and have Weakness?

- Check whether Weakness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xadago:

Xadago (1,022 reports)

Weakness treatments and more:

Weakness (586,876 reports)

Browse all side effects of Xadago:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Weakness:

Weakness (3,641 drugs)

Browse all the conditions that are associated with Weakness:

Weakness (6,611 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on safinamide mesylate (the active ingredients of Xadago) and Xadago (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.