Xalatan and Mydriasis - a phase IV clinical study of FDA data

Summary:

Mydriasis is reported as a side effect among people who take Xalatan (latanoprost), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Timoptic, and have High blood pressure.

The phase IV clinical study analyzes which people have Mydriasis when taking Xalatan. It is created by eHealthMe based on reports of 25,196 people who have side effects when taking Xalatan from the FDA, and is updated regularly.

What is Xalatan?

Xalatan has active ingredients of latanoprost. It is often used in glaucoma. eHealthMe is studying from 25,550 Xalatan users. Check the latest studies of Xalatan.

What is Mydriasis?

Mydriasis (a dilation of the pupil) is found to be associated with 799 drugs and 1,151 conditions by eHealthMe. Check the latest studies of Mydriasis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

25,196 people reported to have side effects when taking Xalatan.
Among them, 33 people (0.13%) have Mydriasis.

Among these 33 people:

How long have people been on Xalatan when they have Mydriasis? *

What is the gender of people who have Mydriasis when taking Xalatan? *

female: 69.7 %
male: 30.3 %

What is the age of people who have Mydriasis when taking Xalatan? *

What are other drugs people take besides Xalatan? *

What are other side effects people have besides Mydriasis? *

Intraocular Pressure Increased: 6 people, 18.18%
Eye Disorder: 5 people, 15.15%
Drug Ineffective: 5 people, 15.15%
Pupillary Reflex Impaired: 5 people, 15.15%
Eyelid Oedema (eyelids are swollen and contain excessive fluid): 4 people, 12.12%
Corneal Oedema (corneal swelling): 3 people, 9.09%
Sensation Of Foreign Body: 3 people, 9.09%
Eye Irritation: 3 people, 9.09%
Pain: 3 people, 9.09%
Feeling Abnormal: 3 people, 9.09%

What are the existing conditions these people have? *

High Blood Pressure: 8 people, 24.24%
Intraocular Pressure Increased: 6 people, 18.18%
Type 1 Diabetes: 3 people, 9.09%
Feeling Of Relaxation: 3 people, 9.09%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 2 people, 6.06%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 6.06%
Intraocular Pressure Test Abnormal: 2 people, 6.06%
Diabetes: 2 people, 6.06%
Vitamin D Decreased: 1 person, 3.03%
Type 2 Diabetes: 1 person, 3.03%

* Approximation only. Some reports may have incomplete information.

Do you take Xalatan and have Mydriasis?

- Check whether Mydriasis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xalatan:

Xalatan (25,550 reports)

Mydriasis treatments and more:

Mydriasis (15,532 reports)

Browse all side effects of Xalatan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mydriasis:

Mydriasis (799 drugs)

Browse all the conditions that are associated with Mydriasis:

Mydriasis (1,151 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on latanoprost (the active ingredients of Xalatan) and Xalatan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.