Xalatan and Raynaud's phenomenon - a phase IV clinical study of FDA data

Summary:

Raynaud's phenomenon is reported as a side effect among people who take Xalatan (latanoprost), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Norvasc, and have Insomnia.

The phase IV clinical study analyzes which people have Raynaud's phenomenon when taking Xalatan. It is created by eHealthMe based on reports of 25,196 people who have side effects when taking Xalatan from the FDA, and is updated regularly.

What is Xalatan?

Xalatan has active ingredients of latanoprost. It is often used in glaucoma. eHealthMe is studying from 25,550 Xalatan users. Check the latest studies of Xalatan.

What is Raynaud's phenomenon?

Raynaud's phenomenon (discoloration of the fingers, toes, and occasionally other areas) is found to be associated with 634 drugs and 995 conditions by eHealthMe. Check the latest studies of Raynaud's phenomenon.

On Jul, 09, 2026

25,196 people reported to have side effects when taking Xalatan.
Among them, 20 people (0.08%) have Raynaud's phenomenon.

Could Xalatan cause Raynaud's phenomenon?

Among these 20 people:

How long have people been on Xalatan when they have Raynaud's phenomenon? *

What is the gender of people who have Raynaud's phenomenon when taking Xalatan? *

female: 60 %
male: 40 %

What is the age of people who have Raynaud's phenomenon when taking Xalatan? *

What are other drugs people take besides Xalatan? *

Xyrem: 7 people, 35.00%
Norvasc: 7 people, 35.00%
Lyrica: 6 people, 30.00%
Atrovent: 6 people, 30.00%
Lunesta: 6 people, 30.00%
Hydroxyzine: 6 people, 30.00%
Fluoxetine: 6 people, 30.00%
Oxycodone And Acetaminophen: 6 people, 30.00%
Dexilant: 6 people, 30.00%
Brintellix: 6 people, 30.00%

What are other side effects people have besides Raynaud's phenomenon? *

Stress And Anxiety: 7 people, 35.00%
Weight Decreased: 7 people, 35.00%
Fall: 7 people, 35.00%
Wrist Fracture: 6 people, 30.00%
Hypoaesthesia (reduced sense of touch or sensation): 6 people, 30.00%
Joint Dislocation (a joint position is changed from normal position): 6 people, 30.00%
Pain In Extremity: 6 people, 30.00%
Quality Of Life Decreased: 6 people, 30.00%
Road Traffic Accident: 6 people, 30.00%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 6 people, 30.00%

What are the existing conditions these people have? *

Insomnia (sleeplessness): 6 people, 30.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 20.00%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 5.00%
Sinusitis (inflammation of sinus): 1 person, 5.00%
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin): 1 person, 5.00%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 5.00%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 1 person, 5.00%
Hypotension (abnormally low blood pressure): 1 person, 5.00%
Eye Infection: 1 person, 5.00%
Cough: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Xalatan and have Raynaud's phenomenon?

- Check whether Raynaud's phenomenon is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xalatan:

Xalatan (25,550 reports)

Browse all side effects of Xalatan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Raynaud's phenomenon:

Raynaud's phenomenon (634 drugs)

Browse all the conditions that are associated with Raynaud's phenomenon:

Raynaud's phenomenon (995 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on latanoprost (the active ingredients of Xalatan) and Xalatan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.