Xalatan and Tibia fracture - a phase IV clinical study of FDA data

Summary:

Tibia fracture is reported as a side effect among people who take Xalatan (latanoprost), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Levothyroxine Sodium, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Tibia fracture when taking Xalatan. It is created by eHealthMe based on reports of 25,196 people who have side effects when taking Xalatan from the FDA, and is updated regularly.

What is Xalatan?

Xalatan has active ingredients of latanoprost. It is often used in glaucoma. eHealthMe is studying from 25,550 Xalatan users. Check the latest studies of Xalatan.

What is Tibia fracture?

Tibia fracture (fracture of lower leg bone) is found to be associated with 642 drugs and 670 conditions by eHealthMe. Check the latest studies of Tibia fracture.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

25,196 people reported to have side effects when taking Xalatan.
Among them, 16 people (0.06%) have Tibia fracture.

$Could Xalatan cause Tibia fracture?$

Among these 16 people:

How long have people been on Xalatan when they have Tibia fracture? *

What is the gender of people who have Tibia fracture when taking Xalatan? *

female: 100 %
male: 0.0 %

What is the age of people who have Tibia fracture when taking Xalatan? *

What are other drugs people take besides Xalatan? *

What are other side effects people have besides Tibia fracture? *

Fall: 7 people, 43.75%
Wrist Fracture: 3 people, 18.75%
Constipation: 3 people, 18.75%
Hypoaesthesia (reduced sense of touch or sensation): 3 people, 18.75%
Foot Fracture: 3 people, 18.75%
Fibula Fracture: 3 people, 18.75%
Femur Fracture: 3 people, 18.75%
Oedema Peripheral (superficial swelling): 3 people, 18.75%
Osteoporosis (bones weak and more likely to break): 3 people, 18.75%
Therapeutic Response Unexpected: 3 people, 18.75%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 37.50%
Osteoporosis (bones weak and more likely to break): 3 people, 18.75%
Uveitis (inflammation of the uvea): 2 people, 12.50%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 12.50%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 12.50%
Osteopenia (a condition where bone mineral density is lower than normal): 2 people, 12.50%
Joint Pain: 2 people, 12.50%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 12.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 12.50%
Constipation: 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Xalatan and have Tibia fracture?

- Check whether Tibia fracture is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xalatan:

Xalatan (25,550 reports)

Tibia fracture treatments and more:

Tibia fracture (6,376 reports)

Browse all side effects of Xalatan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tibia fracture:

Tibia fracture (642 drugs)

Browse all the conditions that are associated with Tibia fracture:

Tibia fracture (670 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on latanoprost (the active ingredients of Xalatan) and Xalatan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.