Xanax and Abnormal weight gain - a phase IV clinical study of FDA data

Summary:

Abnormal weight gain is reported as a side effect among people who take Xanax (alprazolam), especially for people who are female, 60+ old, also take Amitriptyline Hydrochloride, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Abnormal weight gain when taking Xanax. It is created by eHealthMe based on reports of 126,784 people who have side effects when taking Xanax from the FDA, and is updated regularly.

What is Xanax?

Xanax has active ingredients of alprazolam. It is often used in stress and anxiety. eHealthMe is studying from 135,347 Xanax users. Check the latest studies of Xanax.

What is Abnormal weight gain?

Abnormal weight gain is found to be associated with 257 drugs and 708 conditions by eHealthMe. Check the latest studies of Abnormal weight gain.

On Jul, 14, 2026

126,784 people reported to have side effects when taking Xanax.
Among them, 22 people (0.02%) have Abnormal weight gain.

Among these 22 people:

What is the gender of people who have Abnormal weight gain when taking Xanax? *

female: 75 %
male: 25 %

What is the age of people who have Abnormal weight gain when taking Xanax? *

What are other drugs people take besides Xanax? *

Acyclovir: 5 people, 22.73%
Ambien: 5 people, 22.73%
Benadryl: 5 people, 22.73%
Amitriptyline Hydrochloride: 5 people, 22.73%
Synthroid: 4 people, 18.18%
Bactrim: 4 people, 18.18%
Imbruvica: 3 people, 13.64%
Nuvigil: 3 people, 13.64%
Bendamustine Hydrochloride: 3 people, 13.64%
Norco: 3 people, 13.64%

What are other side effects people have besides Abnormal weight gain? *

Fever: 6 people, 27.27%
Rashes (redness): 5 people, 22.73%
Weakness: 5 people, 22.73%
Angioedema (rapid swelling of the dermis): 5 people, 22.73%
Fatigue (feeling of tiredness): 5 people, 22.73%
High Blood Pressure: 5 people, 22.73%
Nausea (feeling of having an urge to vomit): 5 people, 22.73%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 4 people, 18.18%
Dizziness: 4 people, 18.18%
Dyspnea (difficult or laboured breathing): 4 people, 18.18%

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 27.27%
Cardiac Failure Chronic: 5 people, 22.73%
Anaemia (lack of blood): 5 people, 22.73%
Herpes Simplex (herpes simplex is a common viral infection): 5 people, 22.73%
Hyperchlorhydria (gastric acid levels are higher in stomach): 5 people, 22.73%
Rickets (softening of bones): 5 people, 22.73%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 5 people, 22.73%
Burkitt Lymphoma (cancer of the lymphatic system): 5 people, 22.73%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 3 people, 13.64%
Bowel Movement Irregularity: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Xanax and have Abnormal weight gain?

- Check whether Abnormal weight gain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xanax:

Xanax (135,347 reports)

Browse all side effects of Xanax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Abnormal weight gain:

Abnormal weight gain (257 drugs)

Browse all the conditions that are associated with Abnormal weight gain:

Abnormal weight gain (708 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on alprazolam (the active ingredients of Xanax) and Xanax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.