Xanax and Neurological decompensation - a phase IV clinical study of FDA data

Summary:

Neurological decompensation is reported as a side effect among people who take Xanax (alprazolam), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Gleevec, and have Depression.

The phase IV clinical study analyzes which people have Neurological decompensation when taking Xanax. It is created by eHealthMe based on reports of 126,784 people who have side effects when taking Xanax from the FDA, and is updated regularly.

What is Xanax?

Xanax has active ingredients of alprazolam. It is often used in stress and anxiety. eHealthMe is studying from 135,347 Xanax users. Check the latest studies of Xanax.

What is Neurological decompensation?

Neurological decompensation (inability of brain to maintain proper function) is found to be associated with 260 drugs and 451 conditions by eHealthMe. Check the latest studies of Neurological decompensation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

126,784 people reported to have side effects when taking Xanax.
Among them, 18 people (0.01%) have Neurological decompensation.

Could Xanax cause Neurological decompensation?

Among these 18 people:

How long have people been on Xanax when they have Neurological decompensation? *

What is the gender of people who have Neurological decompensation when taking Xanax? *

female: 27.78 %
male: 72.22 %

What is the age of people who have Neurological decompensation when taking Xanax? *

What are other drugs people take besides Xanax? *

What are other side effects people have besides Neurological decompensation? *

Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 5 people, 27.78%
Depression: 4 people, 22.22%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 4 people, 22.22%
Diarrhea: 4 people, 22.22%
Fever: 4 people, 22.22%
Amyotrophic Lateral Sclerosis (nervous system disease that attacks nerve cells called neurons in your brain and spinal cord): 4 people, 22.22%
Hypocalcaemia (levels of calcium in blood serum are abnormally low): 4 people, 22.22%
Ecchymosis (a discoloration of the skin resulting from bleeding underneath): 4 people, 22.22%
Pain: 4 people, 22.22%
Progressive Multifocal Leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells): 4 people, 22.22%

What are the existing conditions these people have? *

Depression: 7 people, 38.89%
High Blood Pressure: 4 people, 22.22%
Diabetes: 4 people, 22.22%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 4 people, 22.22%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 4 people, 22.22%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 3 people, 16.67%
Pain: 2 people, 11.11%
Sleep Disorder: 1 person, 5.56%
Sepsis (a severe blood infection that can lead to organ failure and death): 1 person, 5.56%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Xanax and have Neurological decompensation?

- Check whether Neurological decompensation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xanax:

Xanax (135,347 reports)

Browse all side effects of Xanax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Neurological decompensation:

Neurological decompensation (260 drugs)

Browse all the conditions that are associated with Neurological decompensation:

Neurological decompensation (451 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on alprazolam (the active ingredients of Xanax) and Xanax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.