Xarelto and Bronchospasm aggravated - a phase IV clinical study of FDA data

Summary:

Bronchospasm aggravated is reported as a side effect among people who take Xarelto (rivaroxaban), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Spiriva, and have Asthma.

The phase IV clinical study analyzes which people have Bronchospasm aggravated when taking Xarelto. It is created by eHealthMe based on reports of 210,230 people who have side effects when taking Xarelto from the FDA, and is updated regularly.

What is Xarelto?

Xarelto has active ingredients of rivaroxaban. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 212,377 Xarelto users. Check the latest studies of Xarelto.

What is Bronchospasm aggravated?

Bronchospasm aggravated (spasm of bronchial smooth muscle producing narrowing of the bronchi) is found to be associated with 1,002 drugs and 328 conditions by eHealthMe. Check the latest studies of Bronchospasm aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 27, 2026

210,230 people reported to have side effects when taking Xarelto.
Among them, 76 people (0.04%) have Bronchospasm aggravated.

Could Xarelto cause Bronchospasm aggravated?

Among these 76 people:

How long have people been on Xarelto when they have Bronchospasm aggravated? *

  • < 1 month: 62.5 %
  • 1 - 6 months: 25.0 %
  • 6 - 12 months: 12.5 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Bronchospasm aggravated when taking Xarelto? *

  • female: 64.29 %
  • male: 35.71 %

What is the age of people who have Bronchospasm aggravated when taking Xarelto? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 1.61 %
  • 30-39: 4.84 %
  • 40-49: 16.13 %
  • 50-59: 16.13 %
  • 60+: 61.29 %

What are other drugs people take besides Xarelto? *

  1. Spiriva: 24 people, 31.58%
  2. Alvesco: 19 people, 25.00%
  3. Symbicort: 13 people, 17.11%
  4. Ventolin: 12 people, 15.79%
  5. Xolair: 12 people, 15.79%
  6. Metformin: 10 people, 13.16%
  7. Tamsulosin: 9 people, 11.84%
  8. Crestor: 7 people, 9.21%
  9. Singulair: 7 people, 9.21%
  10. Vitamin B12: 7 people, 9.21%

What are other side effects people have besides Bronchospasm aggravated? *

  1. Dyspnea (difficult or laboured breathing): 41 people, 53.95%
  2. Cough: 30 people, 39.47%
  3. Nasopharyngitis (inflammation of the nasopharynx): 21 people, 27.63%
  4. Wheezing (a high-pitched whistling sound made while you breath): 18 people, 23.68%
  5. Asthma: 18 people, 23.68%
  6. High Blood Pressure: 16 people, 21.05%
  7. Dizziness: 12 people, 15.79%
  8. Mobility Decreased (ability to move is reduced): 12 people, 15.79%
  9. Obstructive Airways Disorder (a progressive disease that makes it hard to breathe): 11 people, 14.47%
  10. Eosinophilia (eosinophil count in the peripheral blood exceeds): 11 people, 14.47%

What are the existing conditions these people have? *

  1. Asthma: 19 people, 25.00%
  2. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 7.89%
  3. Ventricular Extrasystoles (premature cardiac contraction): 6 people, 7.89%
  4. Arrhythmias (irregular heartbeat): 6 people, 7.89%
  5. Nasopharyngitis (inflammation of the nasopharynx): 4 people, 5.26%
  6. Cough: 4 people, 5.26%
  7. Hoarseness Or Changing Voice: 4 people, 5.26%
  8. Chest Pain: 4 people, 5.26%
  9. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 4 people, 5.26%
  10. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung): 4 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Xarelto and have Bronchospasm aggravated?

- Check whether Bronchospasm aggravated is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xarelto:

Bronchospasm aggravated treatments and more:

How severe was Bronchospasm aggravated and when was it recovered:

Expand to all the drugs that have ingredients of rivaroxaban:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xarelto:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bronchospasm aggravated:

Browse all the conditions that are associated with Bronchospasm aggravated:


How the study uses the data?

The study uses data from the FDA. It is based on rivaroxaban (the active ingredients of Xarelto) and Xarelto (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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