Xarelto and Hypertonic bladder - a phase IV clinical study of FDA data

Summary:

Hypertonic bladder is reported as a side effect among people who take Xarelto (rivaroxaban), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Calcium, and have Stress and anxiety.

The phase IV clinical study analyzes which people have Hypertonic bladder when taking Xarelto. It is created by eHealthMe based on reports of 210,230 people who have side effects when taking Xarelto from the FDA, and is updated regularly.

What is Xarelto?

Xarelto has active ingredients of rivaroxaban. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 212,377 Xarelto users. Check the latest studies of Xarelto.

What is Hypertonic bladder?

Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate) is found to be associated with 592 drugs and 520 conditions by eHealthMe. Check the latest studies of Hypertonic bladder.

On Jul, 21, 2026

210,230 people reported to have side effects when taking Xarelto.
Among them, 27 people (0.01%) have Hypertonic bladder.

Among these 27 people:

How long have people been on Xarelto when they have Hypertonic bladder? *

What is the gender of people who have Hypertonic bladder when taking Xarelto? *

female: 73.91 %
male: 26.09 %

What is the age of people who have Hypertonic bladder when taking Xarelto? *

What are other drugs people take besides Xarelto? *

What are other side effects people have besides Hypertonic bladder? *

Fatigue (feeling of tiredness): 14 people, 51.85%
Headache (pain in head): 9 people, 33.33%
Depression: 7 people, 25.93%
Diarrhea: 7 people, 25.93%
Gait Disturbance: 6 people, 22.22%
Vision Blurred: 6 people, 22.22%
Nausea (feeling of having an urge to vomit): 6 people, 22.22%
Malaise (a feeling of general discomfort or uneasiness): 6 people, 22.22%
Joint Pain: 5 people, 18.52%
Oedema Peripheral (superficial swelling): 5 people, 18.52%

What are the existing conditions these people have? *

Stress And Anxiety: 5 people, 18.52%
High Blood Pressure: 4 people, 14.81%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 14.81%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 14.81%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 3 people, 11.11%
Pain: 3 people, 11.11%
Neoplasm Malignant (cancer tumour): 2 people, 7.41%
Herpes Simplex (herpes simplex is a common viral infection): 2 people, 7.41%
Hypophysitis (inflammation of the pituitary gland): 2 people, 7.41%
Diabetes: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Xarelto and have Hypertonic bladder?

- Check whether Hypertonic bladder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xarelto:

Xarelto (212,377 reports)

Browse all side effects of Xarelto:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypertonic bladder:

Hypertonic bladder (592 drugs)

Browse all the conditions that are associated with Hypertonic bladder:

Hypertonic bladder (520 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on rivaroxaban (the active ingredients of Xarelto) and Xarelto (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.