Xarelto and Left ventricular hypertrophy - a phase IV clinical study of FDA data

Summary:

Left ventricular hypertrophy is reported as a side effect among people who take Xarelto (rivaroxaban), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Furosemide, and have Cardiac amyloidosis.

The phase IV clinical study analyzes which people have Left ventricular hypertrophy when taking Xarelto. It is created by eHealthMe based on reports of 210,230 people who have side effects when taking Xarelto from the FDA, and is updated regularly.

What is Xarelto?

Xarelto has active ingredients of rivaroxaban. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 212,377 Xarelto users. Check the latest studies of Xarelto.

What is Left ventricular hypertrophy?

Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart) is found to be associated with 899 drugs and 755 conditions by eHealthMe. Check the latest studies of Left ventricular hypertrophy.

On Jul, 11, 2026

210,230 people reported to have side effects when taking Xarelto.
Among them, 30 people (0.01%) have Left ventricular hypertrophy.

Could Xarelto cause Left ventricular hypertrophy?

Among these 30 people:

How long have people been on Xarelto when they have Left ventricular hypertrophy? *

What is the gender of people who have Left ventricular hypertrophy when taking Xarelto? *

female: 34.48 %
male: 65.52 %

What is the age of people who have Left ventricular hypertrophy when taking Xarelto? *

What are other drugs people take besides Xarelto? *

What are other side effects people have besides Left ventricular hypertrophy? *

Dyspnea (difficult or laboured breathing): 9 people, 30.00%
Mitral Valve Incompetence (inefficient heart valve): 8 people, 26.67%
Left Ventricular Dysfunction: 6 people, 20.00%
Cardiac Failure Chronic: 4 people, 13.33%
Blood Creatinine Increased: 4 people, 13.33%
Ejection Fraction Decreased (systolic heart failure): 4 people, 13.33%
Aortic Arteriosclerosis (hardening of the aortic arteries): 4 people, 13.33%
Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 4 people, 13.33%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 4 people, 13.33%
Cardiac Failure: 4 people, 13.33%

What are the existing conditions these people have? *

Cardiac Amyloidosis (protein deposition in heart): 5 people, 16.67%
Cardiac Failure: 4 people, 13.33%
Blood Pressure Abnormal: 3 people, 10.00%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 6.67%
Multiple Myeloma (cancer of the plasma cells): 2 people, 6.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 6.67%
High Blood Cholesterol: 2 people, 6.67%
Cardiac Disorder: 2 people, 6.67%
Diabetes: 2 people, 6.67%
Asthma: 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Xarelto and have Left ventricular hypertrophy?

- Check whether Left ventricular hypertrophy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xarelto:

Xarelto (212,377 reports)

Browse all side effects of Xarelto:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Left ventricular hypertrophy:

Left ventricular hypertrophy (899 drugs)

Browse all the conditions that are associated with Left ventricular hypertrophy:

Left ventricular hypertrophy (755 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on rivaroxaban (the active ingredients of Xarelto) and Xarelto (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.