Xcopri and Irritability - a phase IV clinical study of FDA data

Summary:

Irritability is reported as a side effect among people who take Xcopri (cenobamate), especially for people who are female, 30-39 old, have been taking the drug for < 1 month also take Klonopin, and have Seizures.

The phase IV clinical study analyzes which people have Irritability when taking Xcopri. It is created by eHealthMe based on reports of 4,132 people who have side effects when taking Xcopri from the FDA, and is updated regularly.

What is Xcopri?

Xcopri has active ingredients of cenobamate. eHealthMe is studying from 4,142 Xcopri users. Check the latest studies of Xcopri.

What is Irritability?

Irritability is found to be associated with 1,700 drugs and 2,458 conditions by eHealthMe. Check the latest studies of Irritability.

On Jul, 20, 2026

4,132 people reported to have side effects when taking Xcopri.
Among them, 47 people (1.14%) have Irritability.

Among these 47 people:

How long have people been on Xcopri when they have Irritability? *

What is the gender of people who have Irritability when taking Xcopri? *

female: 75 %
male: 25 %

What is the age of people who have Irritability when taking Xcopri? *

What are other drugs people take besides Xcopri? *

What are other side effects people have besides Irritability? *

Fatigue (feeling of tiredness): 17 people, 36.17%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 11 people, 23.40%
Drowsiness: 10 people, 21.28%
Depression: 10 people, 21.28%
Balance Disorder: 9 people, 19.15%
Weakness: 8 people, 17.02%
Feeling Abnormal: 6 people, 12.77%
Headache (pain in head): 6 people, 12.77%
Suicidal Ideation: 5 people, 10.64%
Memory Loss: 5 people, 10.64%

What are the existing conditions these people have? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 30 people, 63.83%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 20 people, 42.55%
Simple Partial Seizures (seizures which affect only a small region of the brain): 2 people, 4.26%
Nasopharyngitis (inflammation of the nasopharynx): 2 people, 4.26%
Headache (pain in head): 2 people, 4.26%
Stress And Anxiety: 1 person, 2.13%
Partial Seizures (seizures which affect only a part of the brain at onset): 1 person, 2.13%
Lennox-Gastaut Syndrome (epilepsy characterized by frequent seizures and different seizure types): 1 person, 2.13%
Back Pain: 1 person, 2.13%
Asthma: 1 person, 2.13%

* Approximation only. Some reports may have incomplete information.

Do you take Xcopri and have Irritability?

- Check whether Irritability is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xcopri:

Xcopri (4,142 reports)

Irritability treatments and more:

Irritability (71,614 reports)

Browse all side effects of Xcopri:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Irritability:

Irritability (1,700 drugs)

Browse all the conditions that are associated with Irritability:

Irritability (2,458 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cenobamate (the active ingredients of Xcopri) and Xcopri (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.