Xenical and Oedema - a phase IV clinical study of FDA data

Summary:

Oedema is reported as a side effect among people who take Xenical (orlistat), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Lasix, and have Stress and anxiety.

The phase IV clinical study analyzes which people have Oedema when taking Xenical. It is created by eHealthMe based on reports of 11,562 people who have side effects when taking Xenical from the FDA, and is updated regularly.

What is Xenical?

Xenical has active ingredients of orlistat. It is often used in weight loss. eHealthMe is studying from 11,722 Xenical users. Check the latest studies of Xenical.

What is Oedema?

Oedema (fluid collection in tissue) is found to be associated with 2,181 drugs and 2,311 conditions by eHealthMe. Check the latest studies of Oedema.

On Jul, 20, 2026

11,562 people reported to have side effects when taking Xenical.
Among them, 92 people (0.8%) have Oedema.

Among these 92 people:

How long have people been on Xenical when they have Oedema? *

What is the gender of people who have Oedema when taking Xenical? *

female: 80.22 %
male: 19.78 %

What is the age of people who have Oedema when taking Xenical? *

What are other drugs people take besides Xenical? *

What are other side effects people have besides Oedema? *

Weight Increased: 11 people, 11.96%
Steatorrhea: 11 people, 11.96%
Joint Pain: 10 people, 10.87%
Abdominal Distension: 10 people, 10.87%
Malaise (a feeling of general discomfort or uneasiness): 9 people, 9.78%
Oedema Peripheral (superficial swelling): 9 people, 9.78%
Fever: 9 people, 9.78%
Stress And Anxiety: 8 people, 8.70%
High Blood Pressure: 8 people, 8.70%
Oedema Lower Limb (fluid collection in tissue of lower leg): 8 people, 8.70%

What are the existing conditions these people have? *

Stress And Anxiety: 6 people, 6.52%
Bipolar Disorder (mood disorder): 4 people, 4.35%
Menopause (end of monthly cycles in women): 4 people, 4.35%
Hot Flush (sudden feelings of heat): 3 people, 3.26%
High Blood Pressure: 3 people, 3.26%
Premenstrual Syndrome: 3 people, 3.26%
Cardiac Failure: 2 people, 2.17%
Birth Control: 2 people, 2.17%
Insomnia (sleeplessness): 1 person, 1.09%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 1.09%

* Approximation only. Some reports may have incomplete information.

Do you take Xenical and have Oedema?

- Check whether Oedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xenical:

Xenical (11,722 reports)

Oedema treatments and more:

Oedema (78,747 reports)

Browse all side effects of Xenical:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Oedema:

Oedema (2,181 drugs)

Browse all the conditions that are associated with Oedema:

Oedema (2,311 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on orlistat (the active ingredients of Xenical) and Xenical (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.