Xgeva and Suicidal ideation - a phase IV clinical study of FDA data

Summary:

Suicidal ideation is reported as a side effect among people who take Xgeva (denosumab), especially for people who are male, 60+ old, also take Cymbalta, and have Neoplasm malignant.

The phase IV clinical study analyzes which people have Suicidal ideation when taking Xgeva. It is created by eHealthMe based on reports of 37,636 people who have side effects when taking Xgeva from the FDA, and is updated regularly.

What is Xgeva?

Xgeva has active ingredients of denosumab. It is often used in breast cancer. eHealthMe is studying from 37,717 Xgeva users. Check the latest studies of Xgeva.

What is Suicidal ideation?

Suicidal ideation is found to be associated with 1,980 drugs and 2,342 conditions by eHealthMe. Check the latest studies of Suicidal ideation.

On Jul, 26, 2026

37,636 people reported to have side effects when taking Xgeva.
Among them, 17 people (0.05%) have Suicidal ideation.

Among these 17 people:

What is the gender of people who have Suicidal ideation when taking Xgeva? *

female: 43.75 %
male: 56.25 %

What is the age of people who have Suicidal ideation when taking Xgeva? *

What are other drugs people take besides Xgeva? *

Singulair: 4 people, 23.53%
Cymbalta: 4 people, 23.53%
Calcium: 3 people, 17.65%
Flovent: 3 people, 17.65%
Hydrocodone: 3 people, 17.65%
Hydrocodone Bitartrate And Acetaminophen: 3 people, 17.65%
Keflex: 3 people, 17.65%
Magnesium: 3 people, 17.65%
Melatonin: 3 people, 17.65%
Milk Thistle: 3 people, 17.65%

What are other side effects people have besides Suicidal ideation? *

Pain: 7 people, 41.18%
Dizziness: 5 people, 29.41%
Hallucinations (sensations that appear real but are created by your mind): 4 people, 23.53%
Weight Increased: 4 people, 23.53%
Incontinence (lack of moderation or self-control): 4 people, 23.53%
Back Pain: 4 people, 23.53%
Fatigue (feeling of tiredness): 4 people, 23.53%
Pneumonia: 4 people, 23.53%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 4 people, 23.53%
Depression: 4 people, 23.53%

What are the existing conditions these people have? *

Neoplasm Malignant (cancer tumour): 4 people, 23.53%
Vestibular Disorder (disorders of the body's balance (vestibular) system in the inner ear): 3 people, 17.65%
Panic Disorder: 3 people, 17.65%
Lung Carcinoma Cell Type Unspecified Stage I (the lung cancer is small and hasn't spread to the lymph nodes): 3 people, 17.65%
Muscle Spasms (muscle contraction): 3 people, 17.65%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 3 people, 17.65%
Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 3 people, 17.65%
Renal Cell Carcinoma (a kidney cancer): 3 people, 17.65%
Tinnitus (a ringing in the ears): 3 people, 17.65%
Prostate Cancer: 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

Do you take Xgeva and have Suicidal ideation?

- Check whether Suicidal ideation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xgeva:

Xgeva (37,717 reports)

Suicidal ideation treatments and more:

Suicidal ideation (109,012 reports)

Browse all side effects of Xgeva:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Suicidal ideation:

Suicidal ideation (1,980 drugs)

Browse all the conditions that are associated with Suicidal ideation:

Suicidal ideation (2,342 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on denosumab (the active ingredients of Xgeva) and Xgeva (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.