Xtandi and International normalised ratio abnormal - a phase IV clinical study of FDA data

Summary:

International normalised ratio abnormal is reported as a side effect among people who take Xtandi (enzalutamide), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Pantoprazole, and have Prostate cancer.

The phase IV clinical study analyzes which people have International normalised ratio abnormal when taking Xtandi. It is created by eHealthMe based on reports of 51,433 people who have side effects when taking Xtandi from the FDA, and is updated regularly.

What is Xtandi?

Xtandi has active ingredients of enzalutamide. eHealthMe is studying from 51,498 Xtandi users. Check the latest studies of Xtandi.

What is International normalised ratio abnormal?

International normalised ratio abnormal is found to be associated with 326 drugs and 472 conditions by eHealthMe. Check the latest studies of International normalised ratio abnormal.

On Aug, 02, 2026

51,433 people reported to have side effects when taking Xtandi.
Among them, 31 people (0.06%) have International normalised ratio abnormal.

Could Xtandi cause International normalised ratio abnormal?

Among these 31 people:

How long have people been on Xtandi when they have International normalised ratio abnormal? *

What is the gender of people who have International normalised ratio abnormal when taking Xtandi? *

female: 0.0 %
male: 100 %

What is the age of people who have International normalised ratio abnormal when taking Xtandi? *

What are other drugs people take besides Xtandi? *

What are other side effects people have besides International normalised ratio abnormal? *

Haemoglobin Decreased: 7 people, 22.58%
Fatigue (feeling of tiredness): 7 people, 22.58%
Dyspnea (difficult or laboured breathing): 6 people, 19.35%
Back Pain: 6 people, 19.35%
Peripheral Swelling: 6 people, 19.35%
Drug Ineffective: 5 people, 16.13%
Haemodynamic Instability (disturbances in the blood movement in our body): 5 people, 16.13%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 5 people, 16.13%
Gastritis Erosive (a break in the surface layer of the membrane lining the stomach with infection): 5 people, 16.13%
Gastric Ulcer (stomach ulcer): 5 people, 16.13%

What are the existing conditions these people have? *

Prostate Cancer: 18 people, 58.06%
Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue): 5 people, 16.13%
Prostate Cancer Metastatic: 4 people, 12.90%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 12.90%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 9.68%
Stable Angina (a constant chest pain): 3 people, 9.68%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 1 person, 3.23%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 1 person, 3.23%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 3.23%
High Blood Pressure: 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Xtandi and have International normalised ratio abnormal?

- Check whether International normalised ratio abnormal is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xtandi:

Xtandi (51,498 reports)

International normalised ratio abnormal treatments and more:

International normalised ratio abnormal (4,071 reports)

How severe was International normalised ratio abnormal and when was it recovered:

International normalised ratio abnormal in Xtandi

Expand to all the drugs that have ingredients of enzalutamide:

International normalised ratio abnormal and drugs with ingredients of enzalutamide (48 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xtandi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with International normalised ratio abnormal:

International normalised ratio abnormal (326 drugs)

Browse all the conditions that are associated with International normalised ratio abnormal:

International normalised ratio abnormal (472 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on enzalutamide (the active ingredients of Xtandi) and Xtandi (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.