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Xtandi and Smell - impaired - a phase IV clinical study of FDA data

Summary:

Smell - impaired is reported as a side effect among people who take Xtandi (enzalutamide), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Leukine, and have Prostate cancer.

The phase IV clinical study analyzes which people have Smell - impaired when taking Xtandi. It is created by eHealthMe based on reports of 51,433 people who have side effects when taking Xtandi from the FDA, and is updated regularly.

What is Xtandi?

Xtandi has active ingredients of enzalutamide. eHealthMe is studying from 51,498 Xtandi users. Check the latest studies of Xtandi.

What is Smell - impaired?

Smell - impaired is found to be associated with 647 drugs and 1,211 conditions by eHealthMe. Check the latest studies of Smell - impaired.

On Jul, 18, 2026

51,433 people reported to have side effects when taking Xtandi.
Among them, 20 people (0.04%) have Smell - impaired.

Could Xtandi cause Smell - impaired?

Among these 20 people:

How long have people been on Xtandi when they have Smell - impaired? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Smell - impaired when taking Xtandi? *

  • female: 0.0 %
  • male: 100 %

What is the age of people who have Smell - impaired when taking Xtandi? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

What are other drugs people take besides Xtandi? *

  1. Leukine: 3 people, 15.00%
  2. Vitamin C: 2 people, 10.00%
  3. Paracetamol: 2 people, 10.00%
  4. Metformin: 2 people, 10.00%
  5. Fish Oil: 2 people, 10.00%
  6. Rapaflo: 1 person, 5.00%
  7. Pantoprazole: 1 person, 5.00%
  8. Oxybutynin Chloride: 1 person, 5.00%
  9. Lupron: 1 person, 5.00%
  10. Hydrocodone Bitartrate And Acetaminophen: 1 person, 5.00%

What are other side effects people have besides Smell - impaired? *

  1. Ageusia (loss of taste functions of the tongue): 17 people, 85.00%
  2. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 8 people, 40.00%
  3. Fatigue (feeling of tiredness): 8 people, 40.00%
  4. Drug Ineffective: 5 people, 25.00%
  5. Diarrhea: 3 people, 15.00%
  6. Neck Pain: 3 people, 15.00%
  7. Prostatic Specific Antigen Increased: 3 people, 15.00%
  8. Drowsiness: 2 people, 10.00%
  9. Cough: 2 people, 10.00%
  10. Malaise (a feeling of general discomfort or uneasiness): 2 people, 10.00%

What are the existing conditions these people have? *

  1. Prostate Cancer: 18 people, 90.00%
  2. Neoplasm Prostate (tumour of prostate): 2 people, 10.00%
  3. Prostatic Disorder: 1 person, 5.00%
  4. Prostate Cancer Metastatic: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Xtandi and have Smell - impaired?

- Check whether Smell - impaired is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xtandi:

Smell - impaired treatments and more:

How severe was Smell - impaired and when was it recovered:

Expand to all the drugs that have ingredients of enzalutamide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xtandi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Smell - impaired:

Browse all the conditions that are associated with Smell - impaired:

How the study uses the data?

The study uses data from the FDA. It is based on enzalutamide (the active ingredients of Xtandi) and Xtandi (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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