Xyrem and Appetite disorder - a phase IV clinical study of FDA data

Summary:

Appetite disorder is reported as a side effect among people who take Xyrem (sodium oxybate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Nuvigil, and have Drowsiness.

The phase IV clinical study analyzes which people have Appetite disorder when taking Xyrem. It is created by eHealthMe based on reports of 81,139 people who have side effects when taking Xyrem from the FDA, and is updated regularly.

What is Xyrem?

Xyrem has active ingredients of sodium oxybate. It is often used in narcolepsy. eHealthMe is studying from 81,487 Xyrem users. Check the latest studies of Xyrem.

What is Appetite disorder?

Appetite disorder (abnormal eating habits) is found to be associated with 716 drugs and 706 conditions by eHealthMe. Check the latest studies of Appetite disorder.

On Jul, 14, 2026

81,139 people reported to have side effects when taking Xyrem.
Among them, 44 people (0.05%) have Appetite disorder.

Among these 44 people:

How long have people been on Xyrem when they have Appetite disorder? *

What is the gender of people who have Appetite disorder when taking Xyrem? *

female: 69.23 %
male: 30.77 %

What is the age of people who have Appetite disorder when taking Xyrem? *

What are other drugs people take besides Xyrem? *

What are other side effects people have besides Appetite disorder? *

Stress And Anxiety: 15 people, 34.09%
Insomnia (sleeplessness): 11 people, 25.00%
Weight Decreased: 10 people, 22.73%
Fatigue (feeling of tiredness): 9 people, 20.45%
Memory Loss: 9 people, 20.45%
Nausea (feeling of having an urge to vomit): 8 people, 18.18%
Depression: 7 people, 15.91%
Sleep-Related Eating Disorder (abnormal eating patterns during the night): 6 people, 13.64%
Gait Disturbance: 6 people, 13.64%
Joint Pain: 6 people, 13.64%

What are the existing conditions these people have? *

Drowsiness: 10 people, 22.73%
Depression: 5 people, 11.36%
Hypersensitivity: 5 people, 11.36%
Birth Control: 4 people, 9.09%
Stress And Anxiety: 3 people, 6.82%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 2 people, 4.55%
Sinus Disorder (disease of sinus): 2 people, 4.55%
Nausea (feeling of having an urge to vomit): 2 people, 4.55%
Nasopharyngitis (inflammation of the nasopharynx): 2 people, 4.55%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Xyrem and have Appetite disorder?

- Check whether Appetite disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xyrem:

Xyrem (81,487 reports)

Browse all side effects of Xyrem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Appetite disorder:

Appetite disorder (716 drugs)

Browse all the conditions that are associated with Appetite disorder:

Appetite disorder (706 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sodium oxybate (the active ingredients of Xyrem) and Xyrem (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.