Xyrem and Bulimia - a phase IV clinical study of FDA data

Summary:

Bulimia is reported as a side effect among people who take Xyrem (sodium oxybate), especially for people who are male, 30-39 old, have been taking the drug for 1 - 6 months also take Modafinil, and have Hypothyroidism.

The phase IV clinical study analyzes which people have Bulimia when taking Xyrem. It is created by eHealthMe based on reports of 81,139 people who have side effects when taking Xyrem from the FDA, and is updated regularly.

What is Xyrem?

Xyrem has active ingredients of sodium oxybate. It is often used in narcolepsy. eHealthMe is studying from 81,487 Xyrem users. Check the latest studies of Xyrem.

What is Bulimia?

Bulimia (eating disorder) is found to be associated with 110 drugs and 298 conditions by eHealthMe. Check the latest studies of Bulimia.



On Jul, 12, 2026

81,139 people reported to have side effects when taking Xyrem.
Among them, 22 people (0.03%) have Bulimia.

Could Xyrem cause Bulimia?

Among these 22 people:

How long have people been on Xyrem when they have Bulimia? *

  • < 1 month: 42.86 %
  • 1 - 6 months: 50.0 %
  • 6 - 12 months: 7.14 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Bulimia when taking Xyrem? *

  • female: 42.86 %
  • male: 57.14 %

What is the age of people who have Bulimia when taking Xyrem? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 23.08 %
  • 20-29: 7.69 %
  • 30-39: 53.85 %
  • 40-49: 7.69 %
  • 50-59: 0.0 %
  • 60+: 7.69 %

What are other drugs people take besides Xyrem? *

  1. Modafinil: 6 people, 27.27%
  2. Synthroid: 4 people, 18.18%
  3. Adderall: 4 people, 18.18%
  4. Mobic: 3 people, 13.64%
  5. Nuvigil: 2 people, 9.09%
  6. Oxybutynin: 2 people, 9.09%
  7. Paxil: 2 people, 9.09%
  8. Soma: 2 people, 9.09%
  9. Parnate: 2 people, 9.09%
  10. Thrive: 2 people, 9.09%

What are other side effects people have besides Bulimia? *

  1. Headache (pain in head): 11 people, 50.00%
  2. Weight Decreased: 10 people, 45.45%
  3. Depression: 10 people, 45.45%
  4. Disturbance In Attention: 10 people, 45.45%
  5. Confusional State: 9 people, 40.91%
  6. Insomnia (sleeplessness): 9 people, 40.91%
  7. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 8 people, 36.36%
  8. Sleep Walking (walking during sleep): 8 people, 36.36%
  9. Confusion: 8 people, 36.36%
  10. Psychomotor Hyperactivity (feelings of extreme restlessness): 7 people, 31.82%

What are the existing conditions these people have? *

  1. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 13.64%
  2. Osteoporosis (bones weak and more likely to break): 1 person, 4.55%
  3. Drowsiness: 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Xyrem and have Bulimia?

- Check whether Bulimia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xyrem:

Bulimia treatments and more:

How severe was Bulimia and when was it recovered:

Expand to all the drugs that have ingredients of sodium oxybate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xyrem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bulimia:

Browse all the conditions that are associated with Bulimia:


How the study uses the data?

The study uses data from the FDA. It is based on sodium oxybate (the active ingredients of Xyrem) and Xyrem (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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