Xyrem and Scratch - a phase IV clinical study of FDA data
Summary:
Scratch is reported as a side effect among people who take Xyrem (sodium oxybate), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Cymbalta, and have Drowsiness.
The phase IV clinical study analyzes which people have Scratch when taking Xyrem. It is created by eHealthMe based on reports of 81,139 people who have side effects when taking Xyrem from the FDA, and is updated regularly.
What is Xyrem?
Xyrem has active ingredients of sodium oxybate. It is often used in narcolepsy. eHealthMe is studying from 81,487 Xyrem users. Check the latest studies of Xyrem.
What is Scratch?
Scratch is found to be associated with 693 drugs and 745 conditions by eHealthMe. Check the latest studies of Scratch.
81,139 people reported to have side effects when taking Xyrem.
Among them, 45 people (0.06%) have Scratch.

Among these 45 people:
How long have people been on Xyrem when they have Scratch? *
- < 1 month: 45.45 %
- 1 - 6 months: 40.91 %
- 6 - 12 months: 4.55 %
- 1 - 2 years: 9.09 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Scratch when taking Xyrem? *
- female: 84.44 %
- male: 15.56 %
What is the age of people who have Scratch when taking Xyrem? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 20 %
- 30-39: 5 %
- 40-49: 20 %
- 50-59: 35 %
- 60+: 20 %
What are other drugs people take besides Xyrem? *
- Cymbalta: 12 people, 26.67%
- Adderall: 7 people, 15.56%
- Gabapentin: 5 people, 11.11%
- Ativan: 5 people, 11.11%
- Prevacid: 5 people, 11.11%
- Synthroid: 5 people, 11.11%
- Promethazine: 4 people, 8.89%
- Magnesium Carbonate: 4 people, 8.89%
- Singulair: 4 people, 8.89%
- Luxiq: 4 people, 8.89%
What are other side effects people have besides Scratch? *
- Hallucinations (sensations that appear real but are created by your mind): 11 people, 24.44%
- Fall: 11 people, 24.44%
- Dizziness: 8 people, 17.78%
- Head Injury: 8 people, 17.78%
- Stress And Anxiety: 8 people, 17.78%
- Itching: 7 people, 15.56%
- Drowsiness: 5 people, 11.11%
- Weight Increased: 5 people, 11.11%
- Gait Disturbance: 5 people, 11.11%
- Therapeutic Response Unexpected: 5 people, 11.11%
What are the existing conditions these people have? *
- Drowsiness: 7 people, 15.56%
- Hypersensitivity: 4 people, 8.89%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.67%
- Multiple Allergies (allergy to multiple agents): 3 people, 6.67%
- Asthma: 3 people, 6.67%
- Rickets (softening of bones): 3 people, 6.67%
- Hyperhidrosis (abnormally increased sweating): 2 people, 4.44%
- Allergy To Animal: 2 people, 4.44%
- Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 2 people, 4.44%
- Arrhythmias (irregular heartbeat): 2 people, 4.44%
* Approximation only. Some reports may have incomplete information.
Do you take Xyrem and have Scratch?
- Check whether Scratch is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Xyrem:
- Xyrem (81,487 reports)
Scratch treatments and more:
- Scratch (10,633 reports)
How severe was Scratch and when was it recovered:
Expand to all the drugs that have ingredients of sodium oxybate:
- Scratch and drugs with ingredients of sodium oxybate (40 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Xyrem:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Scratch:
- Scratch (693 drugs)
Browse all the conditions that are associated with Scratch:
- Scratch (745 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on sodium oxybate (the active ingredients of Xyrem) and Xyrem (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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