Xyzal and Glaucoma - a phase IV clinical study of FDA data

Summary:

Glaucoma is reported as a side effect among people who take Xyzal (levocetirizine dihydrochloride), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Lopressor, and have High blood pressure.

The phase IV clinical study analyzes which people have Glaucoma when taking Xyzal. It is created by eHealthMe based on reports of 20,548 people who have side effects when taking Xyzal from the FDA, and is updated regularly.

What is Xyzal?

Xyzal has active ingredients of levocetirizine dihydrochloride. It is often used in allergies. eHealthMe is studying from 21,479 Xyzal users. Check the latest studies of Xyzal.

What is Glaucoma?

Glaucoma (increased fluid pressure in the eye with vision loss) is found to be associated with 1,234 drugs and 1,656 conditions by eHealthMe. Check the latest studies of Glaucoma.

On Jul, 20, 2026

20,548 people reported to have side effects when taking Xyzal.
Among them, 33 people (0.16%) have Glaucoma.

Among these 33 people:

How long have people been on Xyzal when they have Glaucoma? *

What is the gender of people who have Glaucoma when taking Xyzal? *

female: 51.61 %
male: 48.39 %

What is the age of people who have Glaucoma when taking Xyzal? *

What are other drugs people take besides Xyzal? *

What are other side effects people have besides Glaucoma? *

Osteoarthritis (a joint disease caused by cartilage loss in a joint): 17 people, 51.52%
Cataract (clouding of the lens inside the eye): 17 people, 51.52%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 14 people, 42.42%
Back Pain: 14 people, 42.42%
Intervertebral Disc Degeneration (spinal disc degeneration): 14 people, 42.42%
Dyspnea (difficult or laboured breathing): 14 people, 42.42%
Stress And Anxiety: 14 people, 42.42%
Lumbar Spine Flattening (flatten the curve of the lower spine): 13 people, 39.39%
Inflammation: 13 people, 39.39%
Intervertebral Disc Protrusion (spinal disc protrusion): 13 people, 39.39%

What are the existing conditions these people have? *

High Blood Pressure: 13 people, 39.39%
Metastasis (spreadable cancer to other organ from origin): 8 people, 24.24%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 12.12%
Hypersensitivity: 4 people, 12.12%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 4 people, 12.12%
Urticaria (rash of round, red welts on the skin that itch intensely): 4 people, 12.12%
Sinusitis (inflammation of sinus): 4 people, 12.12%
Headache (pain in head): 3 people, 9.09%
Depression: 3 people, 9.09%
Ankylosing Spondylitis (type of arthritis affecting the spine): 3 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Xyzal and have Glaucoma?

- Check whether Glaucoma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xyzal:

Xyzal (21,479 reports)

Glaucoma treatments and more:

Glaucoma (61,926 reports)

How severe was Glaucoma and when was it recovered:

Glaucoma in Xyzal

Expand to all the drugs that have ingredients of levocetirizine dihydrochloride:

Glaucoma and drugs with ingredients of levocetirizine dihydrochloride (43 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xyzal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Glaucoma:

Glaucoma (1,234 drugs)

Browse all the conditions that are associated with Glaucoma:

Glaucoma (1,656 conditions)

Related publications that referenced our studies

Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .
Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .

How the study uses the data?

The study uses data from the FDA. It is based on levocetirizine dihydrochloride (the active ingredients of Xyzal) and Xyzal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.