Yaz and Breast swelling - a phase IV clinical study of FDA data

Summary:

Breast swelling is reported as a side effect among people who take Yaz (drospirenone; ethinyl estradiol), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Mirena, and have Fibromyalgia.

The phase IV clinical study analyzes which people have Breast swelling when taking Yaz. It is created by eHealthMe based on reports of 39,984 people who have side effects when taking Yaz from the FDA, and is updated regularly.

What is Yaz?

Yaz has active ingredients of drospirenone; ethinyl estradiol. It is often used in birth control. eHealthMe is studying from 41,514 Yaz users. Check the latest studies of Yaz.

What is Breast swelling?

Breast swelling is found to be associated with 285 drugs and 472 conditions by eHealthMe. Check the latest studies of Breast swelling.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

39,984 people reported to have side effects when taking Yaz.
Among them, 14 people (0.04%) have Breast swelling.

Among these 14 people:

How long have people been on Yaz when they have Breast swelling? *

What is the gender of people who have Breast swelling when taking Yaz? *

female: 100 %
male: 0.0 %

What is the age of people who have Breast swelling when taking Yaz? *

What are other drugs people take besides Yaz? *

What are other side effects people have besides Breast swelling? *

Abdominal Distension: 5 people, 35.71%
Weight Increased: 4 people, 28.57%
Breast Pain: 4 people, 28.57%
Nausea (feeling of having an urge to vomit): 3 people, 21.43%
Weakness: 3 people, 21.43%
Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 21.43%
Fatigue (feeling of tiredness): 3 people, 21.43%
Stress And Anxiety: 3 people, 21.43%
Dyspnea (difficult or laboured breathing): 3 people, 21.43%
Diarrhea: 2 people, 14.29%

What are the existing conditions these people have? *

Weakness: 1 person, 7.14%
Seasonal Allergy (allergic condition due to certain season): 1 person, 7.14%
Post Procedural Complication: 1 person, 7.14%
Muscle Spasms (muscle contraction): 1 person, 7.14%
Menstruation Irregular: 1 person, 7.14%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Yaz and have Breast swelling?

- Check whether Breast swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Yaz:

Yaz (41,514 reports)

Breast swelling treatments and more:

Breast swelling (2,966 reports)

How severe was Breast swelling and when was it recovered:

Breast swelling in Yaz

Expand to all the drugs that have ingredients of drospirenone; ethinyl estradiol:

Breast swelling and drugs with ingredients of drospirenone; ethinyl estradiol (39 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Yaz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Breast swelling:

Breast swelling (285 drugs)

Browse all the conditions that are associated with Breast swelling:

Breast swelling (472 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on drospirenone; ethinyl estradiol (the active ingredients of Yaz) and Yaz (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.